PedAM

Pediatric Disease Annotations & Medicines


	hepatitis b

Disease ID	536
Disease	hepatitis b
Definition	INFLAMMATION of the LIVER in humans caused by a member of the ORTHOHEPADNAVIRUS genus, HEPATITIS B VIRUS. It is primarily transmitted by parenteral exposure, such as transfusion of contaminated blood or blood products, but can also be transmitted via sexual or intimate personal contact.
Synonym	b viral hepatitis hbv hepatitis b [disease/finding] hepatitis b infection hepatitis b viral hepatitis viral b hepatitis, serum serum hepatitis serum hepatitis (disorder) sh - serum hepatitis type b viral hepatitis type b viral hepatitis (disorder) viral hepatitis b viral hepatitis type b viral hepatitis type b (disorder) viral serum hepatitis b viral serum hepatitis b (disorder)
DOID	DOID:2043
UMLS	C0019163
MeSH	D006509
SNOMED-CT	SNOMEDCT_US_2016_09_01:66071002
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:217) C0023890 \| cirrhosis \| 156 C0019204 \| hepatocellular carcinoma \| 150 C0023895 \| liver disease \| 70 C0023890 \| liver cirrhosis \| 67 C0019158 \| hepatitis \| 60 C0019196 \| hepatitis c \| 29 C0024299 \| lymphoma \| 22 C0042769 \| viral infection \| 20 C0011847 \| diabetes \| 13 C0023903 \| liver cancer \| 12 C0011226 \| hepatitis d \| 12 C0042721 \| viral hepatitis \| 11 C0003864 \| arthritis \| 10 C0021831 \| bowel disease \| 9 C0023895 \| liver diseases \| 9 C0021390 \| inflammatory bowel disease \| 9 C0011849 \| diabetes mellitus \| 8 C0003873 \| rheumatoid arthritis \| 8 C0022658 \| kidney disease \| 7 C0035078 \| renal failure \| 6 C0948265 \| metabolic syndrome \| 6 C0022661 \| chronic kidney disease \| 6 C0019204 \| hepatoma \| 5 C0017665 \| membranous nephropathy \| 5 C0017658 \| glomerulonephritis \| 5 C0085293 \| hepatitis e \| 5 C0079731 \| b-cell lymphoma \| 5 C0019163 \| hepatitis b \| 5 C0079744 \| diffuse large b-cell lymphoma \| 5 C0019204 \| hepatocellular carcinomas \| 4 C0042769 \| viral infections \| 4 C0019163 \| hepatitis b infection \| 4 C0026764 \| myeloma \| 4 C0020538 \| hypertension \| 4 C0026764 \| multiple myeloma \| 4 C0042769 \| virus infection \| 4 C0206698 \| cholangiocarcinoma \| 4 C0031036 \| polyarteritis nodosa \| 4 C0022661 \| end-stage renal disease \| 4 C0026848 \| myopathy \| 4 C0022658 \| nephropathy \| 4 C0409974 \| lupus erythematosus \| 4 C0376545 \| hematological malignancies \| 4 C0022658 \| renal disease \| 4 C0018916 \| hemangioma \| 3 C0042384 \| vasculitis \| 3 C0023646 \| lichen planus \| 3 C0024305 \| non-hodgkin lymphoma \| 3 C0024141 \| systemic lupus erythematosus \| 3 C0019196 \| hepatitis c infection \| 3 C0019829 \| hodgkin lymphoma \| 3 C0022661 \| chronic renal failure \| 3 C0007570 \| celiac disease \| 3 C0023418 \| leukemia \| 3 C0027726 \| nephrotic syndrome \| 3 C0015624 \| fanconi syndrome \| 3 C0039128 \| syphilis \| 3 C0001973 \| alcoholism \| 3 C1565489 \| renal insufficiency \| 3 C0011570 \| depression \| 3 C0345905 \| intrahepatic cholangiocarcinoma \| 3 C0029134 \| optic neuritis \| 2 C0242647 \| mucosa-associated lymphoid tissue lymphoma \| 2 C0033860 \| psoriasis \| 2 C0008372 \| intrahepatic cholestasis \| 2 C0033687 \| proteinuria \| 2 C0241910 \| autoimmune hepatitis \| 2 C0025202 \| melanoma \| 2 C0031154 \| peritonitis \| 2 C0025289 \| meningitis \| 2 C0040053 \| thrombosis \| 2 C0001430 \| adenoma \| 2 C0020541 \| portal hypertension \| 2 C0024115 \| pulmonary disease \| 2 C0042345 \| varices \| 2 C0010403 \| cryoglobulinemia \| 2 C0027868 \| neuromuscular disorders \| 2 C0024117 \| chronic obstructive pulmonary disease \| 2 C0021359 \| infertility \| 2 C0024314 \| lymphoproliferative disorders \| 2 C0085655 \| polymyositis \| 2 C0024314 \| lymphoproliferative disorder \| 2 C0023890 \| hepatic cirrhosis \| 2 C0021364 \| male infertility \| 2 C0026848 \| muscular disorders \| 2 C0002170 \| alopecia \| 2 C0016053 \| fibromyalgia \| 2 C0025007 \| measles \| 2 C0019829 \| hodgkin's lymphoma \| 2 C0014867 \| esophageal varices \| 2 C0006142 \| breast cancer \| 2 C0035435 \| rheumatic disease \| 2 C0027813 \| neuritis \| 2 C0442874 \| neuropathy \| 2 C0376545 \| hematological malignancy \| 1 C0242363 \| islet cell tumor \| 1 C0010346 \| crohn's disease \| 1 C0238301 \| nasopharyngeal carcinoma \| 1 C0021053 \| immune disease \| 1 C0035435 \| rheumatic diseases \| 1 C0024299 \| lymphomas \| 1 C0025286 \| meningioma \| 1 C0019045 \| hemoglobinopathies \| 1 C0008370 \| bile duct obstruction \| 1 C0016470 \| food allergy \| 1 C0014059 \| acute disseminated encephalomyelitis \| 1 C1621958 \| glioblastoma multiforme \| 1 C0013502 \| hydatid disease \| 1 C0004623 \| bacterial infection \| 1 C0041296 \| tuberculosis \| 1 C0949690 \| spondyloarthritis \| 1 C0004096 \| asthma \| 1 C0024299 \| malignant lymphoma \| 1 C0024623 \| gastric cancer \| 1 C0085404 \| poems syndrome \| 1 C0085436 \| cryptococcal meningitis \| 1 C0003467 \| anxiety \| 1 C0020532 \| hypersplenism \| 1 C0018801 \| heart failure \| 1 C0079731 \| b-cell non-hodgkin lymphoma \| 1 C0017665 \| membranous glomerulonephritis \| 1 C0600260 \| obstructive pulmonary disease \| 1 C0023895 \| hepatic disease \| 1 C0017168 \| oesophageal reflux \| 1 C0555198 \| malignant glioma \| 1 C0032285 \| pneumonia \| 1 C0242647 \| malt lymphoma \| 1 C0040147 \| thyroiditis \| 1 C0242647 \| mucosa-associated lymphoid tissue \| 1 C0271650 \| prediabetes \| 1 C0037198 \| sinus thrombosis \| 1 C0022660 \| acute renal failure \| 1 C0085434 \| bacillary angiomatosis \| 1 C0861876 \| recurrent hepatocellular carcinoma \| 1 C0021400 \| influenza \| 1 C0019360 \| herpes zoster \| 1 C0024530 \| malaria \| 1 C0009241 \| cognitive disorders \| 1 C1261473 \| sarcoma \| 1 C0017662 \| membranoproliferative glomerulonephritis \| 1 C0011854 \| type i diabetes mellitus \| 1 C0494491 \| mononeuropathy \| 1 C0018920 \| cavernous hemangioma \| 1 C0035078 \| kidney failure \| 1 C0023492 \| t-cell leukemia \| 1 C0040128 \| thyroid disorders \| 1 C0023448 \| lymphocytic leukemia \| 1 C0019360 \| zoster \| 1 C0030807 \| pemphigus \| 1 C1527336 \| sjogren's syndrome \| 1 C0014179 \| uterine infection \| 1 C0040034 \| thrombocytopenia \| 1 C0024305 \| non-hodgkin's lymphoma \| 1 C0006017 \| pertussis \| 1 C0038358 \| gastric ulcer \| 1 C0024301 \| follicular lymphoma \| 1 C0023493 \| adult t-cell leukemia-lymphoma \| 1 C0002726 \| amyloidosis \| 1 C0038358 \| gastric ulcers \| 1 C0376545 \| hematologic malignancy \| 1 C0023470 \| myeloid leukemia \| 1 C0041327 \| pulmonary tuberculosis \| 1 C0022661 \| end-stage renal failure \| 1 C0017636 \| glioblastoma \| 1 C1561644 \| chronic kidney disease (ckd) \| 1 C0267841 \| acalculous cholecystitis \| 1 C0009324 \| ulcerative colitis \| 1 C0238246 \| liver hemangioma \| 1 C0004030 \| aspergillosis \| 1 C0023903 \| liver tumor \| 1 C0023467 \| acute myeloid leukemia \| 1 C0008325 \| cholecystitis \| 1 C0038012 \| spondylitis \| 1 C0235618 \| proliferative glomerulonephritis \| 1 C0009319 \| colitis \| 1 C0025286 \| meningiomas \| 1 C0002880 \| autoimmune hemolytic anemia \| 1 C0011854 \| type i diabetes \| 1 C0011633 \| dermatomyositis \| 1 C0017168 \| gastroesophageal reflux \| 1 C0021359 \| infertile \| 1 C0010631 \| cystadenocarcinoma \| 1 C0011226 \| delta hepatitis \| 1 C0085253 \| adult-onset still's disease \| 1 C0221757 \| alpha 1-antitrypsin deficiency \| 1 C0023434 \| chronic lymphocytic leukemia \| 1 C0038013 \| ankylosing spondylitis \| 1 C0000786 \| miscarriage \| 1 C0015230 \| rash \| 1 C0023343 \| leprosy \| 1 C0023493 \| adult t-cell leukemia \| 1 C1112746 \| hepatic lymphoma \| 1 C0040149 \| subacute thyroiditis \| 1 C0014070 \| encephalomyelitis \| 1 C0023891 \| alcoholic liver cirrhosis \| 1 C0019151 \| hepatic encephalopathy \| 1 C0002878 \| hemolytic anemia \| 1 C0019204 \| hepatocarcinoma \| 1 C0042164 \| uveitis \| 1 C0152025 \| polyneuropathy \| 1 C0039730 \| thalassemia \| 1 C0004153 \| atherosclerosis \| 1 C0003872 \| psoriatic arthritis \| 1 C0017168 \| esophageal reflux \| 1 C0019163 \| serum hepatitis \| 1 C0028754 \| obesity \| 1 C0036323 \| schistosomiasis \| 1 C0024117 \| chronic obstructive pulmonary disease (copd) \| 1 C0004352 \| autism \| 1 C0017168 \| esophageal reflux disease \| 1 C0019212 \| hepatorenal syndrome \| 1 C0008370 \| cholestasis \| 1 C0002871 \| anemia \| 1 C0002871 \| anaemia \| 1 C0023891 \| alcoholic cirrhosis \| 1 C0017168 \| gastroesophageal reflux disease \| 1 C0271650 \| glucose intolerance \| 1
Curated Gene	Entrez_id \| Symbol \| Resource(Total Genes:16) GRIN2A \| 2903 \| GWASCAT IFNAR2 \| 3455 \| CTD_human IFNG \| 3458 \| CTD_human HLA-DPA1 \| 3113 \| GWASCAT HLA-DPB1 \| 3115 \| GWASCAT HP \| 3240 \| CTD_human UBE2L3 \| 7332 \| GWASCAT IFNA2 \| 3440 \| CTD_human CYP2A6 \| 1548 \| CTD_human LOX \| 4015 \| CTD_human IL10RB \| 3588 \| CTD_human IFNGR1 \| 3459 \| CTD_human IFNB1 \| 3456 \| CTD_human IFNA1 \| 3439 \| CTD_human LOXL2 \| 4017 \| CTD_human SLC10A1 \| 6554 \| CTD_human
Inferring Gene	Entrez_id \| Symbol \| Resource(Total Genes:60) 103 \| ADAR \| infer 348 \| APOE \| infer 6352 \| CCL5 \| infer 1234 \| CCR5 \| infer 958 \| CD40 \| infer 960 \| CD44 \| infer 965 \| CD58 \| infer 998 \| CDC42 \| infer 4261 \| CIITA \| infer 6387 \| CXCL12 \| infer 5610 \| EIF2AK2 \| infer 1965 \| EIF2S1 \| infer 1998 \| ELF2 \| infer 2634 \| GBP2 \| infer 27201 \| GPR78 \| infer 2903 \| GRIN2A \| infer 3105 \| HLA-A \| infer 3106 \| HLA-B \| infer 3107 \| HLA-C \| infer 3115 \| HLA-DPB1 \| infer 3117 \| HLA-DQA1 \| infer 3119 \| HLA-DQB1 \| infer 3123 \| HLA-DRB1 \| infer 3440 \| IFNA2 \| infer 3454 \| IFNAR1 \| infer 3458 \| IFNG \| infer 3459 \| IFNGR1 \| infer 3460 \| IFNGR2 \| infer 3586 \| IL10 \| infer 3587 \| IL10RA \| infer 3593 \| IL12B \| infer 3606 \| IL18 \| infer 29949 \| IL19 \| infer 3554 \| IL1R1 \| infer 3558 \| IL2 \| infer 3565 \| IL4 \| infer 3566 \| IL4R \| infer 3569 \| IL6 \| infer 3659 \| IRF1 \| infer 3716 \| JAK1 \| infer 4049 \| LTA \| infer 4153 \| MBL2 \| infer 4155 \| MBP \| infer 4314 \| MMP3 \| infer 4318 \| MMP9 \| infer 4524 \| MTHFR \| infer 4552 \| MTRR \| infer 4599 \| MX1 \| infer 4938 \| OAS1 \| infer 4939 \| OAS2 \| infer 4940 \| OAS3 \| infer 5696 \| PSMB8 \| infer 5698 \| PSMB9 \| infer 6772 \| STAT1 \| infer 6890 \| TAP1 \| infer 6891 \| TAP2 \| infer 30009 \| TBX21 \| infer 7040 \| TGFB1 \| infer 7124 \| TNF \| infer 7421 \| VDR \| infer
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:534) 57291 \| DANCR \| DISEASES 138948 \| DBH-AS1 \| DISEASES 10942 \| PRSS21 \| DISEASES 920 \| CD4 \| DISEASES 3385 \| ICAM3 \| DISEASES 7132 \| TNFRSF1A \| DISEASES 3028 \| HSD17B10 \| DISEASES 30009 \| TBX21 \| DISEASES 27248 \| ERLEC1 \| DISEASES 23505 \| TMEM131 \| DISEASES 3902 \| LAG3 \| DISEASES 350 \| APOH \| DISEASES 4616 \| GADD45B \| DISEASES 11274 \| USP18 \| DISEASES 57026 \| PDXP \| DISEASES 80339 \| PNPLA3 \| DISEASES 3002 \| GZMB \| DISEASES 6554 \| SLC10A1 \| DISEASES 4792 \| NFKBIA \| DISEASES 57167 \| SALL4 \| DISEASES 3929 \| LBP \| DISEASES 51311 \| TLR8 \| DISEASES 2158 \| F9 \| DISEASES 7076 \| TIMP1 \| DISEASES 4313 \| MMP2 \| DISEASES 221191 \| PRSS54 \| DISEASES 171177 \| RHOV \| DISEASES 2137 \| EXTL3 \| DISEASES 7038 \| TG \| DISEASES 8797 \| TNFRSF10A \| DISEASES 54793 \| KCTD9 \| DISEASES 2091 \| FBL \| DISEASES 1178 \| CLC \| DISEASES 7040 \| TGFB1 \| DISEASES 973 \| CD79A \| DISEASES 1048 \| CEACAM5 \| DISEASES 57817 \| HAMP \| DISEASES 3082 \| HGF \| DISEASES 10135 \| NAMPT \| DISEASES 727 \| C5 \| DISEASES 6348 \| CCL3 \| DISEASES 1440 \| CSF3 \| DISEASES 1362 \| CPD \| DISEASES 6347 \| CCL2 \| DISEASES 952 \| CD38 \| DISEASES 3381 \| IBSP \| DISEASES 3558 \| IL2 \| DISEASES 3312 \| HSPA8 \| DISEASES 969 \| CD69 \| DISEASES 51561 \| IL23A \| DISEASES 4055 \| LTBR \| DISEASES 3458 \| IFNG \| DISEASES 2597 \| GAPDH \| DISEASES 3111 \| HLA-DOA \| DISEASES 3565 \| IL4 \| DISEASES 3567 \| IL5 \| DISEASES 662 \| BNIP1 \| DISEASES 338 \| APOB \| DISEASES 4759 \| NEU2 \| DISEASES 5657 \| PRTN3 \| DISEASES 6402 \| SELL \| DISEASES 335 \| APOA1 \| DISEASES 7276 \| TTR \| DISEASES 2703 \| GJA8 \| DISEASES 8743 \| TNFSF10 \| DISEASES 56829 \| ZC3HAV1 \| DISEASES 28981 \| IFT81 \| DISEASES 6626 \| SNRPA \| DISEASES 4109 \| MAGEA10 \| DISEASES 718 \| C3 \| DISEASES 1236 \| CCR7 \| DISEASES 4708 \| NDUFB2 \| DISEASES 10875 \| FGL2 \| DISEASES 2678 \| GGT1 \| DISEASES 2952 \| GSTT1 \| DISEASES 200315 \| APOBEC3A \| DISEASES 84316 \| NAA38 \| DISEASES 968 \| CD68 \| DISEASES 6351 \| CCL4 \| DISEASES 3630 \| INS \| DISEASES 6674 \| SPAG1 \| DISEASES 5894 \| RAF1 \| DISEASES 2056 \| EPO \| DISEASES 1571 \| CYP2E1 \| DISEASES 9104 \| RGN \| DISEASES 2161 \| F12 \| DISEASES 23225 \| NUP210 \| DISEASES 23378 \| RRP8 \| DISEASES 1401 \| CRP \| DISEASES 29958 \| DMGDH \| DISEASES 3845 \| KRAS \| DISEASES 2947 \| GSTM3 \| DISEASES 10542 \| LAMTOR5 \| DISEASES 8933 \| FAM127A \| DISEASES 29969 \| MDFIC \| DISEASES 3569 \| IL6 \| DISEASES 3557 \| IL1RN \| DISEASES 3442 \| IFNA5 \| DISEASES 7097 \| TLR2 \| DISEASES 9360 \| PPIG \| DISEASES 7450 \| VWF \| DISEASES 217 \| ALDH2 \| DISEASES 2184 \| FAH \| DISEASES 114294 \| LACTB \| DISEASES 9972 \| NUP153 \| DISEASES 9172 \| MYOM2 \| DISEASES 4591 \| TRIM37 \| DISEASES 8312 \| AXIN1 \| DISEASES 6521 \| SLC4A1 \| DISEASES 3959 \| LGALS3BP \| DISEASES 25939 \| SAMHD1 \| DISEASES 7515 \| XRCC1 \| DISEASES 22858 \| ICK \| DISEASES 23523 \| CABIN1 \| DISEASES 4924 \| NUCB1 \| DISEASES 3553 \| IL1B \| DISEASES 23476 \| BRD4 \| DISEASES 5067 \| CNTN3 \| DISEASES 4072 \| EPCAM \| DISEASES 10578 \| GNLY \| DISEASES 23095 \| KIF1B \| DISEASES 3299 \| HSF4 \| DISEASES 941 \| CD80 \| DISEASES 56925 \| LXN \| DISEASES 590 \| BCHE \| DISEASES 59067 \| IL21 \| DISEASES 1356 \| CP \| DISEASES 6774 \| STAT3 \| DISEASES 7297 \| TYK2 \| DISEASES 3383 \| ICAM1 \| DISEASES 64083 \| GOLPH3 \| DISEASES 1390 \| CREM \| DISEASES 127 \| ADH4 \| DISEASES 63898 \| SH2D4A \| DISEASES 51608 \| GET4 \| DISEASES 3700 \| ITIH4 \| DISEASES 56938 \| ARNTL2 \| DISEASES 939 \| CD27 \| DISEASES 51411 \| BIN2 \| DISEASES 60314 \| C12orf10 \| DISEASES 11057 \| ABHD2 \| DISEASES 5045 \| FURIN \| DISEASES 432 \| ASGR1 \| DISEASES 7157 \| TP53 \| DISEASES 5409 \| PNMT \| DISEASES 56006 \| SMG9 \| DISEASES 3454 \| IFNAR1 \| DISEASES 207 \| AKT1 \| DISEASES 9869 \| SETDB1 \| DISEASES 3756 \| KCNH1 \| DISEASES 2052 \| EPHX1 \| DISEASES 9515 \| STXBP5L \| DISEASES 167410 \| LIX1 \| DISEASES 3578 \| IL9 \| DISEASES 170954 \| PPP1R18 \| DISEASES 134864 \| TAAR1 \| DISEASES 4841 \| NONO \| DISEASES 55909 \| BIN3 \| DISEASES 3439 \| IFNA1 \| DISEASES 23082 \| PPRC1 \| DISEASES 51075 \| TMX2 \| DISEASES 149986 \| LSM14B \| DISEASES 117153 \| MIA2 \| DISEASES 3606 \| IL18 \| DISEASES 54842 \| MFSD6 \| DISEASES 636 \| BICD1 \| DISEASES 7292 \| TNFSF4 \| DISEASES 5741 \| PTH \| DISEASES 22925 \| PLA2R1 \| DISEASES 925 \| CD8A \| DISEASES 231 \| AKR1B1 \| DISEASES 9154 \| SLC28A1 \| DISEASES 10563 \| CXCL13 \| DISEASES 3588 \| IL10RB \| DISEASES 2220 \| FCN2 \| DISEASES 23547 \| LILRA4 \| DISEASES 9437 \| NCR1 \| DISEASES 643 \| CXCR5 \| DISEASES 55585 \| UBE2Q1 \| DISEASES 1234 \| CCR5 \| DISEASES 10898 \| CPSF4 \| DISEASES 3046 \| HBE1 \| DISEASES 6352 \| CCL5 \| DISEASES 3856 \| KRT8 \| DISEASES 2215 \| FCGR3B \| DISEASES 27306 \| HPGDS \| DISEASES 3577 \| CXCR1 \| DISEASES 213 \| ALB \| DISEASES 7047 \| TGM4 \| DISEASES 308 \| ANXA5 \| DISEASES 3600 \| IL15 \| DISEASES 6228 \| RPS23 \| DISEASES 4724 \| NDUFS4 \| DISEASES 9607 \| CARTPT \| DISEASES 7098 \| TLR3 \| DISEASES 1437 \| CSF2 \| DISEASES 168667 \| BMPER \| DISEASES 3429 \| IFI27 \| DISEASES 7184 \| HSP90B1 \| DISEASES 5347 \| PLK1 \| DISEASES 54760 \| PCSK4 \| DISEASES 1642 \| DDB1 \| DISEASES 27258 \| LSM3 \| DISEASES 140838 \| NANP \| DISEASES 3479 \| IGF1 \| DISEASES 3308 \| HSPA4 \| DISEASES 23788 \| MTCH2 \| DISEASES 1493 \| CTLA4 \| DISEASES 3094 \| HINT1 \| DISEASES 375611 \| SLC26A5 \| DISEASES 3627 \| CXCL10 \| DISEASES 3575 \| IL7R \| DISEASES 149603 \| RNF187 \| DISEASES 3669 \| ISG20 \| DISEASES 125 \| ADH1B \| DISEASES 56246 \| MRAP \| DISEASES 6373 \| CXCL11 \| DISEASES 646 \| BNC1 \| DISEASES 4247 \| MGAT2 \| DISEASES 144125 \| OR2AG1 \| DISEASES 27087 \| B3GAT1 \| DISEASES 2752 \| GLUL \| DISEASES 10855 \| HPSE \| DISEASES 2147 \| F2 \| DISEASES 9940 \| DLEC1 \| DISEASES 5340 \| PLG \| DISEASES 1212 \| CLTB \| DISEASES 7015 \| TERT \| DISEASES 200316 \| APOBEC3F \| DISEASES 6868 \| ADAM17 \| DISEASES 947 \| CD34 \| DISEASES 3661 \| IRF3 \| DISEASES 5708 \| PSMD2 \| DISEASES 92597 \| MOB1B \| DISEASES 8302 \| KLRC4 \| DISEASES 27243 \| CHMP2A \| DISEASES 2944 \| GSTM1 \| DISEASES 84868 \| HAVCR2 \| DISEASES 5319 \| PLA2G1B \| DISEASES 3952 \| LEP \| DISEASES 3172 \| HNF4A \| DISEASES 51593 \| SRRT \| DISEASES 9153 \| SLC28A2 \| DISEASES 30835 \| CD209 \| DISEASES 6773 \| STAT2 \| DISEASES 8560 \| DEGS1 \| DISEASES 23512 \| SUZ12 \| DISEASES 4233 \| MET \| DISEASES 4684 \| NCAM1 \| DISEASES 7173 \| TPO \| DISEASES 29851 \| ICOS \| DISEASES 80381 \| CD276 \| DISEASES 2193 \| FARSA \| DISEASES 9370 \| ADIPOQ \| DISEASES 25898 \| RCHY1 \| DISEASES 51582 \| AZIN1 \| DISEASES 10611 \| PDLIM5 \| DISEASES 6014 \| RIT2 \| DISEASES 2274 \| FHL2 \| DISEASES 2 \| A2M \| DISEASES 3309 \| HSPA5 \| DISEASES 3032 \| HADHB \| DISEASES 27107 \| ZBTB11 \| DISEASES 79228 \| THOC6 \| DISEASES 9582 \| APOBEC3B \| DISEASES 8784 \| TNFRSF18 \| DISEASES 3855 \| KRT7 \| DISEASES 50616 \| IL22 \| DISEASES 3665 \| IRF7 \| DISEASES 8651 \| SOCS1 \| DISEASES 84206 \| MEX3B \| DISEASES 9021 \| SOCS3 \| DISEASES 9146 \| HGS \| DISEASES 440097 \| DBX2 \| DISEASES 54328 \| GPR173 \| DISEASES 942 \| CD86 \| DISEASES 1485 \| CTAG1B \| DISEASES 29796 \| UQCR10 \| DISEASES 5104 \| SERPINA5 \| DISEASES 3916 \| LAMP1 \| DISEASES 51807 \| TUBA8 \| DISEASES 340075 \| ARSI \| DISEASES 151888 \| BTLA \| DISEASES 3043 \| HBB \| DISEASES 2152 \| F3 \| DISEASES 220001 \| VWCE \| DISEASES 54490 \| UGT2B28 \| DISEASES 196528 \| ARID2 \| DISEASES 5133 \| PDCD1 \| DISEASES 3320 \| HSP90AA1 \| DISEASES 8653 \| DDX3Y \| DISEASES 3802 \| KIR2DL1 \| DISEASES 7189 \| TRAF6 \| DISEASES 1576 \| CYP3A4 \| DISEASES 3824 \| KLRD1 \| DISEASES 10239 \| AP3S2 \| DISEASES 3266 \| ERAS \| DISEASES 5329 \| PLAUR \| DISEASES 3117 \| HLA-DQA1 \| DISEASES 3805 \| KIR2DL4 \| DISEASES 23708 \| GSPT2 \| DISEASES 2029 \| ENSA \| DISEASES 1544 \| CYP1A2 \| DISEASES 259197 \| NCR3 \| DISEASES 3804 \| KIR2DL3 \| DISEASES 2305 \| FOXM1 \| DISEASES 6672 \| SP100 \| DISEASES 3146 \| HMGB1 \| DISEASES 84552 \| PARD6G \| DISEASES 3455 \| IFNAR2 \| DISEASES 3605 \| IL17A \| DISEASES 1499 \| CTNNB1 \| DISEASES 84706 \| GPT2 \| DISEASES 1861 \| TOR1A \| DISEASES 302 \| ANXA2 \| DISEASES 3921 \| RPSA \| DISEASES 5562 \| PRKAA1 \| DISEASES 91653 \| BOC \| DISEASES 355 \| FAS \| DISEASES 5265 \| SERPINA1 \| DISEASES 6720 \| SREBF1 \| DISEASES 2074 \| ERCC6 \| DISEASES 3240 \| HP \| DISEASES 84502 \| JPH4 \| DISEASES 10905 \| MAN1A2 \| DISEASES 85320 \| ABCC11 \| DISEASES 4100 \| MAGEA1 \| DISEASES 60 \| ACTB \| DISEASES 4343 \| MOV10 \| DISEASES 5169 \| ENPP3 \| DISEASES 11148 \| HHLA2 \| DISEASES 10987 \| COPS5 \| DISEASES 6775 \| STAT4 \| DISEASES 389376 \| SFTA2 \| DISEASES 3821 \| KLRC1 \| DISEASES 9332 \| CD163 \| DISEASES 1786 \| DNMT1 \| DISEASES 3123 \| HLA-DRB1 \| DISEASES 7037 \| TFRC \| DISEASES 2157 \| F8 \| DISEASES 3135 \| HLA-G \| DISEASES 5599 \| MAPK8 \| DISEASES 54106 \| TLR9 \| DISEASES 2530 \| FUT8 \| DISEASES 6772 \| STAT1 \| DISEASES 4512 \| MT-CO1 \| DISEASES 2475 \| MTOR \| DISEASES 10256 \| CNKSR1 \| DISEASES 4283 \| CXCL9 \| DISEASES 7096 \| TLR1 \| DISEASES 23137 \| SMC5 \| DISEASES 3880 \| KRT19 \| DISEASES 1378 \| CR1 \| DISEASES 1660 \| DHX9 \| DISEASES 6041 \| RNASEL \| DISEASES 84946 \| LTV1 \| DISEASES 462 \| SERPINC1 \| DISEASES 356 \| FASLG \| DISEASES 3459 \| IFNGR1 \| DISEASES 1805 \| DPT \| DISEASES 10767 \| HBS1L \| DISEASES 22926 \| ATF6 \| DISEASES 127943 \| FCRLB \| DISEASES 2214 \| FCGR3A \| DISEASES 1490 \| CTGF \| DISEASES 51744 \| CD244 \| DISEASES 9447 \| AIM2 \| DISEASES 912 \| CD1D \| DISEASES 115350 \| FCRL1 \| DISEASES 3570 \| IL6R \| DISEASES 1892 \| ECHS1 \| DISEASES 7062 \| TCHH \| DISEASES 79626 \| TNFAIP8L2 \| DISEASES 8349 \| HIST2H2BE \| DISEASES 914 \| CD2 \| DISEASES 965 \| CD58 \| DISEASES 4102 \| MAGEA3 \| DISEASES 959 \| CD40LG \| DISEASES 3725 \| JUN \| DISEASES 116151 \| FAM210B \| DISEASES 7422 \| VEGFA \| DISEASES 958 \| CD40 \| DISEASES 4318 \| MMP9 \| DISEASES 5328 \| PLAU \| DISEASES 55315 \| SLC29A3 \| DISEASES 54577 \| UGT1A7 \| DISEASES 2833 \| CXCR3 \| DISEASES 7099 \| TLR4 \| DISEASES 246184 \| CDC26 \| DISEASES 1269 \| CNR2 \| DISEASES 316 \| AOX1 \| DISEASES 3108 \| HLA-DMA \| DISEASES 229 \| ALDOB \| DISEASES 3118 \| HLA-DQA2 \| DISEASES 3127 \| HLA-DRB5 \| DISEASES 2245 \| FGD1 \| DISEASES 221527 \| ZBTB12 \| DISEASES 10919 \| EHMT2 \| DISEASES 2155 \| F7 \| DISEASES 728239 \| MAGED4 \| DISEASES 3304 \| HSPA1B \| DISEASES 57819 \| LSM2 \| DISEASES 53358 \| SHC3 \| DISEASES 3055 \| HCK \| DISEASES 10673 \| TNFSF13B \| DISEASES 9358 \| ITGBL1 \| DISEASES 50943 \| FOXP3 \| DISEASES 100507436 \| MICA \| DISEASES 3107 \| HLA-C \| DISEASES 64078 \| SLC28A3 \| DISEASES 6941 \| TCF19 \| DISEASES 7133 \| TNFRSF1B \| DISEASES 729956 \| SHISA7 \| DISEASES 3133 \| HLA-E \| DISEASES 3105 \| HLA-A \| DISEASES 10257 \| ABCC4 \| DISEASES 1471 \| CST3 \| DISEASES 23670 \| TMEM2 \| DISEASES 6461 \| SHB \| DISEASES 8718 \| TNFRSF25 \| DISEASES 4609 \| MYC \| DISEASES 3400 \| ID4 \| DISEASES 53940 \| FTHL17 \| DISEASES 9308 \| CD83 \| DISEASES 2625 \| GATA3 \| DISEASES 9636 \| ISG15 \| DISEASES 4499 \| MT1M \| DISEASES 23586 \| DDX58 \| DISEASES 3559 \| IL2RA \| DISEASES 10346 \| TRIM22 \| DISEASES 3440 \| IFNA2 \| DISEASES 3456 \| IFNB1 \| DISEASES 3030 \| HADHA \| DISEASES 51284 \| TLR7 \| DISEASES 1646 \| AKR1C2 \| DISEASES 1645 \| AKR1C1 \| DISEASES 4267 \| CD99 \| DISEASES 90865 \| IL33 \| DISEASES 29126 \| CD274 \| DISEASES 3822 \| KLRC2 \| DISEASES 91543 \| RSAD2 \| DISEASES 51091 \| SEPSECS \| DISEASES 9681 \| DEPDC5 \| DISEASES 7750 \| ZMYM2 \| DISEASES 6736 \| SRY \| DISEASES 8618 \| CADPS \| DISEASES 51280 \| GOLM1 \| DISEASES 399664 \| MEX3D \| DISEASES 3875 \| KRT18 \| DISEASES 167227 \| DCP2 \| DISEASES 5799 \| PTPRN2 \| DISEASES 3811 \| KIR3DL1 \| DISEASES 80196 \| RNF34 \| DISEASES 29994 \| BAZ2B \| DISEASES 51466 \| EVL \| DISEASES 2719 \| GPC3 \| DISEASES 5866 \| RAB3IL1 \| DISEASES 2875 \| GPT \| DISEASES 6696 \| SPP1 \| DISEASES 3122 \| HLA-DRA \| DISEASES 3965 \| LGALS9 \| DISEASES 174 \| AFP \| DISEASES 83989 \| FAM172A \| DISEASES 55233 \| MOB1A \| DISEASES 10379 \| IRF9 \| DISEASES 80380 \| PDCD1LG2 \| DISEASES 4599 \| MX1 \| DISEASES 2950 \| GSTP1 \| DISEASES 3119 \| HLA-DQB1 \| DISEASES 1763 \| DNA2 \| DISEASES 1654 \| DDX3X \| DISEASES 3803 \| KIR2DL2 \| DISEASES 6654 \| SOS1 \| DISEASES 60489 \| APOBEC3G \| DISEASES 51270 \| TFDP3 \| DISEASES 2115 \| ETV1 \| DISEASES 728441 \| GGT2 \| DISEASES 7018 \| TF \| DISEASES 4052 \| LTBP1 \| DISEASES 1363 \| CPE \| DISEASES 93986 \| FOXP2 \| DISEASES 23066 \| CAND2 \| DISEASES 4938 \| OAS1 \| DISEASES 3120 \| HLA-DQB2 \| DISEASES 4495 \| MT1G \| DISEASES 3481 \| IGF2 \| DISEASES 3113 \| HLA-DPA1 \| DISEASES 3447 \| IFNA13 \| DISEASES 1029 \| CDKN2A \| DISEASES 720 \| C4A \| DISEASES 55665 \| URGCP \| DISEASES 91975 \| ZNF300 \| DISEASES 3702 \| ITK \| DISEASES 7124 \| TNF \| DISEASES 3106 \| HLA-B \| DISEASES 4615 \| MYD88 \| DISEASES 4049 \| LTA \| DISEASES 6892 \| TAPBP \| DISEASES 388372 \| CCL4L1 \| DISEASES 3115 \| HLA-DPB1 \| DISEASES 1154 \| CISH \| DISEASES 4050 \| LTB \| DISEASES 23658 \| LSM5 \| DISEASES 3451 \| IFNA17 \| DISEASES 3586 \| IL10 \| DISEASES 55758 \| RCOR3 \| DISEASES 51763 \| INPP5K \| DISEASES 6229 \| RPS24 \| DISEASES 4193 \| MDM2 \| DISEASES 3077 \| HFE \| DISEASES 5515 \| PPP2CA \| DISEASES 27042 \| DIEXF \| DISEASES 5478 \| PPIA \| DISEASES 10209 \| EIF1 \| DISEASES 30816 \| ERVW-1 \| DISEASES 11267 \| SNF8 \| DISEASES 51428 \| DDX41 \| DISEASES 79772 \| MCTP1 \| DISEASES 2197 \| FAU \| DISEASES 930 \| CD19 \| DISEASES 586 \| BCAT1 \| DISEASES 7421 \| VDR \| DISEASES 9051 \| PSTPIP1 \| DISEASES 567 \| B2M \| DISEASES 11245 \| GPR176 \| DISEASES 101 \| ADAM8 \| DISEASES 284424 \| MIR7-3HG \| DISEASES 246734 \| NPCDR1 \| DISEASES 594842 \| HAS2-AS1 \| DISEASES 79104 \| MEG8 \| DISEASES 677769 \| SCARNA17 \| DISEASES 94161 \| SNORD46 \| DISEASES 26800 \| SNORD49A \| DISEASES 101669766 \| ZNF350-AS1 \| DISEASES
Locus	(Waiting for update.)

Disease ID	536
Disease	hepatitis b
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:126) HP:0001394 \| Hepatic cirrhosis \| 156 HP:0001402 \| Hepatocellular carcinoma \| 149 HP:0030731 \| Carcinoma \| 138 HP:0012115 \| Liver inflammation \| 66 HP:0200123 \| Chronic liver inflammation \| 40 HP:0001399 \| Liver failure \| 35 HP:0002665 \| Lymphoma \| 22 HP:0001395 \| Hepatic fibrosis \| 19 HP:0002896 \| Liver cancer \| 13 HP:0006554 \| Acute hepatic failure \| 13 HP:0001397 \| Hepatic steatosis \| 12 HP:0002664 \| Neoplasia \| 11 HP:0006562 \| Viral hepatitis \| 11 HP:0001369 \| Arthritis \| 10 HP:0001370 \| Rheumatoid arthritis \| 8 HP:0000083 \| Renal insufficiency \| 8 HP:0003774 \| End-stage renal failure \| 8 HP:0000819 \| Diabetes mellitus \| 8 HP:0100626 \| Chronic hepatic failure \| 7 HP:0002721 \| Immunodeficiency \| 6 HP:0012622 \| Chronic kidney disease \| 6 HP:0004448 \| Fulminant hepatic failure \| 6 HP:0012578 \| Membranous glomerulonephritis \| 6 HP:0012189 \| Hodgkin disease \| 5 HP:0012191 \| B-cell lymphoma \| 5 HP:0000099 \| Glomerular nephritis \| 5 HP:0000822 \| Hypertension \| 4 HP:0200119 \| Acute liver inflammation \| 4 HP:0004787 \| Fulminant hepatitis \| 4 HP:0000112 \| Nephropathy \| 4 HP:0003198 \| Myopathic changes \| 4 HP:0006775 \| Multiple myeloma \| 4 HP:0030153 \| Cholangiocarcinoma \| 4 HP:0000716 \| Depression \| 3 HP:0001028 \| Strawberry mark \| 3 HP:0001909 \| Leukemia \| 3 HP:0012539 \| Non-Hodgkin lymphoma \| 3 HP:0000855 \| Insulin resistance \| 3 HP:0000952 \| Yellow skin \| 3 HP:0000100 \| Nephrosis \| 3 HP:0002633 \| Vasculitis \| 3 HP:0002725 \| Systemic lupus erythematosus \| 3 HP:0002608 \| Celiac disease \| 3 HP:0002148 \| Hypophosphataemia \| 3 HP:0001541 \| Ascites \| 3 HP:0001903 \| Anemia \| 2 HP:0100653 \| Optic neuritis \| 2 HP:0002861 \| Melanoma \| 2 HP:0000093 \| Proteinuria \| 2 HP:0001298 \| Encephalopathy \| 2 HP:0003002 \| Breast carcinoma \| 2 HP:0006510 \| Chronic obstructive pulmonary disease \| 2 HP:0005523 \| Lymphoproliferative disorder \| 2 HP:0100778 \| Cryoglobulinemia \| 2 HP:0002910 \| Elevated transaminases \| 2 HP:0001596 \| Hair loss \| 2 HP:0001409 \| Portal hypertension \| 2 HP:0000789 \| Infertility \| 2 HP:0001406 \| Intrahepatic cholestasis \| 2 HP:0002586 \| Peritonitis \| 2 HP:0003765 \| Psoriasis \| 2 HP:0003251 \| Male infertility \| 2 HP:0001287 \| Meningitis \| 2 HP:0002099 \| Asthma \| 1 HP:0012579 \| Minimal change glomerulonephritis \| 1 HP:0002904 \| High blood bilirubin levels \| 1 HP:0000554 \| Uveitis \| 1 HP:0002592 \| Stomach ulcer \| 1 HP:0005364 \| Severe viral infections \| 1 HP:0012531 \| Pain \| 1 HP:0000833 \| Glucose intolerance \| 1 HP:0100545 \| Arterial stenosis \| 1 HP:0002858 \| Mengiomia \| 1 HP:0005435 \| Impaired T cell function \| 1 HP:0012126 \| Gastric cancer \| 1 HP:0001513 \| Obesity \| 1 HP:0100242 \| Sarcoma \| 1 HP:0010702 \| Hypergammaglobulinaemia \| 1 HP:0000708 \| Behavioral problems \| 1 HP:0003256 \| Coagulopathy \| 1 HP:0003324 \| Muscle weakness, diffuse \| 1 HP:0000729 \| Pervasive developmental disorder \| 1 HP:0001048 \| Cavernous angioma \| 1 HP:0001410 \| Decreased liver function \| 1 HP:0100033 \| Tic disorder \| 1 HP:0011947 \| Respiratory infection \| 1 HP:0002090 \| Pneumonia \| 1 HP:0001396 \| Cholestasis \| 1 HP:0003613 \| Antiphospholipid antibodies \| 1 HP:0002960 \| Autoimmune condition \| 1 HP:0001971 \| Hypersplenism \| 1 HP:0009831 \| Single damaged nerve \| 1 HP:0012594 \| High urine albumin levels \| 1 HP:0000717 \| Autism \| 1 HP:0005550 \| Chronic lymphatic leukemia \| 1 HP:0100843 \| Glioblastoma \| 1 HP:0030248 \| Blood clot in mesentertic vein \| 1 HP:0003073 \| Hypoalbuminaemia \| 1 HP:0002480 \| Hepatic encephalopathy \| 1 HP:0000793 \| Membranoproliferative glomerulonephritis \| 1 HP:0002621 \| Atherosclerosis \| 1 HP:0012324 \| Myeloid leukemia \| 1 HP:0001890 \| Autoimmune hemolytic anemia \| 1 HP:0012190 \| T cell lymphoma \| 1 HP:0000157 \| Abnormality of the tongue \| 1 HP:0200120 \| Chronic active hepatitis \| 1 HP:0100279 \| Ulcerative colitis \| 1 HP:0001878 \| Haemolytic anaemia \| 1 HP:0002020 \| Heartburn \| 1 HP:0100806 \| Sepsis \| 1 HP:0004808 \| Acute myelogenous leukemia \| 1 HP:0001873 \| Low platelet count \| 1 HP:0012174 \| Glioblastoma multiforme \| 1 HP:0100651 \| Type I diabetes mellitus \| 1 HP:0001082 \| Cholecystitis \| 1 HP:0002955 \| Granulomatosis \| 1 HP:0001271 \| Polyneuropathy \| 1 HP:0001919 \| Acute renal failure \| 1 HP:0001635 \| Congestive heart failure \| 1 HP:0000739 \| Anxiety \| 1 HP:0100845 \| Anaphylactic shock \| 1 HP:0100646 \| Thyroiditis \| 1 HP:0001324 \| Muscular weakness \| 1 HP:0004936 \| Blood clot in vein \| 1 HP:0011034 \| Amyloid disease \| 1 HP:0002583 \| Colitis \| 1

Disease ID	536
Disease	hepatitis b
Manually Symptom	(Waiting for update.)
Text Mined Symptom	UMLS \| Name \| Sentences' Count(Total Symptoms:70) C0009450 \| infection \| 596 C0151317 \| chronic infection \| 209 C0019204 \| hepatocellular carcinoma \| 143 C0023890 \| cirrhosis \| 125 C0021311 \| infections \| 87 C0239946 \| liver fibrosis \| 80 C0023895 \| liver disease \| 65 C0019189 \| chronic hepatitis \| 33 C0023890 \| liver cirrhosis \| 32 C0019196 \| hepatitis c \| 29 C0085605 \| liver failure \| 26 C0042769 \| viral infection \| 20 C0239946 \| hepatic fibrosis \| 19 C0341439 \| chronic liver disease \| 18 C1264606 \| persistent infection \| 16 C0011226 \| hepatitis d \| 12 C0023903 \| liver cancer \| 12 C0042721 \| viral hepatitis \| 11 C0038826 \| superinfection \| 10 C0162557 \| acute liver failure \| 10 C0796095 \| c syndrome \| 9 C0085605 \| hepatic failure \| 9 C0011849 \| diabetes mellitus \| 8 C0042749 \| viremia \| 7 C0275518 \| acute infection \| 7 C0162557 \| fulminant hepatic failure \| 6 C0276623 \| chronic viral hepatitis \| 5 C0017658 \| glomerulonephritis \| 5 C0426768 \| o sign \| 5 C0017665 \| membranous nephropathy \| 5 C0023895 \| liver diseases \| 4 C0267797 \| acute hepatitis \| 4 C0042769 \| virus infection \| 4 C0031036 \| polyarteritis nodosa \| 4 C0302809 \| fulminant hepatitis \| 4 C0009450 \| infectious disease \| 4 C0022658 \| renal disease \| 4 C0022346 \| jaundice \| 3 C0039128 \| syphilis \| 3 C0042384 \| vasculitis \| 3 C0027726 \| nephrotic syndrome \| 3 C0235378 \| hepatotoxicity \| 3 C0021079 \| immunosuppression \| 2 C0019204 \| hepatocellular carcinomas \| 2 C0020541 \| portal hypertension \| 2 C0275551 \| spontaneous bacterial peritonitis \| 2 C0162557 \| acute hepatic failure \| 2 C0008372 \| intrahepatic cholestasis \| 2 C0042345 \| varices \| 2 C0027868 \| neuromuscular disorders \| 2 C0442874 \| neuropathy \| 2 C0010403 \| cryoglobulinemia \| 2 C0162323 \| polyarthritis \| 1 C0019693 \| human immunodeficiency virus infection \| 1 C0022660 \| acute renal failure \| 1 C0011633 \| dermatomyositis \| 1 C1112211 \| liver infection \| 1 C0520463 \| chronic active hepatitis \| 1 C0152025 \| polyneuropathy \| 1 C0580174 \| portal hypertensive gastropathy \| 1 C0079772 \| t-cell lymphoma \| 1 C0019151 \| hepatic encephalopathy \| 1 C1112157 \| intrauterine infection \| 1 C0343190 \| cutaneous polyarteritis nodosa \| 1 C0017662 \| membranoproliferative glomerulonephritis \| 1 C0086110 \| delta superinfection \| 1 C0730345 \| microalbuminuria \| 1 C0149519 \| chronic persistent hepatitis \| 1 C0242647 \| malt lymphoma \| 1 C0162557 \| fulminant liver failure \| 1

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:157)
snpId	pubmedId	geneId	geneSymbol	diseaseId	sourceId	sentence	score	Year	geneSymbol_dbSNP	CHROMOSOME	POS	REF	ALT
rs10053538	22587604	84868	HAVCR2	umls:C0019163	BeFree	These findings suggest that -1516G/T polymorphism in the promoter region of TIM3 gene may affect the disease susceptibility and HCC traits associated with HBV infection, potentially supporting the role of Tim-3 in T-cell dysfunction and exhaustion involved in persistent HBV infection and HCC development.	0.002171535	2012	HAVCR2	5	157110499	C	A,T
rs1012068	25032264	3588	IL10RB	umls:C0019163	BeFree	Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.	0.120814326	2015	DEPDC5	22	31869917	T	G
rs1012068	25032264	390928	PAPL	umls:C0019163	BeFree	Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.	0.000271442	2015	DEPDC5	22	31869917	T	G
rs1042522	18390844	7157	TP53	umls:C0019163	BeFree	Thus, MDM2 SNP 309 and p53 Arg72Pro are associated with the early development of HCC in Korean patients with chronic HBV infection.	0.037065441	2008	TP53	17	7676154	G	T,C
rs1042522	18390844	4193	MDM2	umls:C0019163	BeFree	Thus, MDM2 SNP 309 and p53 Arg72Pro are associated with the early development of HCC in Korean patients with chronic HBV infection.	0.001085767	2008	TP53	17	7676154	G	T,C
rs1057035	23868705	23405	DICER1	umls:C0019163	BeFree	We observed that DICER1 rs1057035 CT/CC variant genotypes were associated with a significant decreased risk of HCC (adjusted OR = 0.79, 95% CI = 0.64-0.96) compared with wild-type TT and RAN rs3803012 AG/GG variant genotypes increased the risk of HBV persistent infection compared with AA genotype (adjusted OR = 1.35, 95% CI = 1.03-1.77).	0.000271442	2013	DICER1	14	95087805	T	C
rs1057035	23868705	9271	PIWIL1	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	DICER1	14	95087805	T	C
rs1057035	23868705	5901	RAN	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	DICER1	14	95087805	T	C
rs10773771	23868705	5901	RAN	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	PIWIL1	12	130371771	C	T
rs10773771	23868705	9271	PIWIL1	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	PIWIL1	12	130371771	C	T
rs10912564	22536368	7292	TNFSF4	umls:C0019163	BeFree	Three SNPs (rs12133337 and rs10918706 in CD3Z, rs10912564 in OX40L) were associated significantly with the immune response to hepatitis B vaccination (P = 0.008, 0.041, and 0.019, respectively).	0.000271442	2012	TNFSF4	1	173201479	C	T
rs10918706	22536368	7292	TNFSF4	umls:C0019163	BeFree	Three SNPs (rs12133337 and rs10918706 in CD3Z, rs10912564 in OX40L) were associated significantly with the immune response to hepatitis B vaccination (P = 0.008, 0.041, and 0.019, respectively).	0.000271442	2012	CD247;LOC101928512	1	167496884	C	T
rs114465251	22015712	3135	HLA-G	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.000814326	2012	NA	NA	NA	NA	NA
rs114465251	22015712	3133	HLA-E	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.00434307	2012	NA	NA	NA	NA	NA
rs11540654	18390844	4193	MDM2	umls:C0019163	BeFree	Thus, MDM2 SNP 309 and p53 Arg72Pro are associated with the early development of HCC in Korean patients with chronic HBV infection.	0.001085767	2008	TP53	17	7676040	C	T,G,A
rs11540654	18390844	7157	TP53	umls:C0019163	BeFree	Thus, MDM2 SNP 309 and p53 Arg72Pro are associated with the early development of HCC in Korean patients with chronic HBV infection.	0.037065441	2008	TP53	17	7676040	C	T,G,A
rs115492845	22015712	3133	HLA-E	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.00434307	2012	NA	NA	NA	NA	NA
rs115492845	22015712	3135	HLA-G	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.000814326	2012	NA	NA	NA	NA	NA
rs11549465	25195037	3091	HIF1A	umls:C0019163	BeFree	Two polymorphisms in the HIF-1a gene (rs11549465 and rs115494657) were examined in 157 hepatitis B virus (HBV)-related HCC patients and 173 healthy controls using the polymerase chain reaction-restriction fragment length polymorphism method.	0.006263026	2014	HIF1A;LOC105370526	14	61740839	C	T
rs11866328	22004137	2903	GRIN2A	umls:C0019163	BeFree	A genome-wide association study with DNA pooling identifies the variant rs11866328 in the GRIN2A gene that affects disease progression of chronic HBV infection.	0.122638474	2011	GRIN2A	16	9768699	G	T
rs11866328	22004137	2903	GRIN2A	umls:C0019163	GWASCAT	A genome-wide association study with DNA pooling identifies the variant rs11866328 in the GRIN2A gene that affects disease progression of chronic HBV infection.	0.122638474	2011	GRIN2A	16	9768699	G	T
rs11866328	22004137	2903	GRIN2A	umls:C0019163	GAD	[A genome-wide association study with DNA pooling identifies the variant rs11866328 in the GRIN2A gene that affects disease progression of chronic HBV infection.]	0.122638474	2011	GRIN2A	16	9768699	G	T
rs12133337	22536368	7292	TNFSF4	umls:C0019163	BeFree	Three SNPs (rs12133337 and rs10918706 in CD3Z, rs10912564 in OX40L) were associated significantly with the immune response to hepatitis B vaccination (P = 0.008, 0.041, and 0.019, respectively).	0.000271442	2012	CD247;LOC101928512	1	167483453	T	C
rs12375841	22658643	406894	MIR101-2	umls:C0019163	BeFree	In addition, rs12375841 and its unique haplotype (ht2) in miR-101-2 show significant association with clearance of hepatitis B virus infection.	0.000271442	2012	RCL1;MIR101-2	9	4850141	T	C
rs12979860	22239156	282617	IFNL3	umls:C0019163	BeFree	IL28B rs12979860 polymorphism does not influence outcomes of hepatitis B virus infection.	0.008957582	2012	IFNL3;IFNL4	19	39248147	C	T
rs12979860	25219480	282617	IFNL3	umls:C0019163	BeFree	In recipients carrying rs12979860 IL-28B C/C genotype the use of cyclosporine seems to contribute to enhance the probability of developing biliary complications which in hepatitis B and C positives appear to reduce patient survival.	0.008957582	2014	IFNL3;IFNL4	19	39248147	C	T
rs12979860	25391769	282617	IFNL3	umls:C0019163	BeFree	Frequency of interleukin 28B rs12979860 C>T variants in Filipino patients chronically infected with hepatitis B virus.	0.008957582	2014	IFNL3;IFNL4	19	39248147	C	T
rs12979860	24874053	282617	IFNL3	umls:C0019163	BeFree	Genetic variation of interleukin-28B (IL-28B) rs12979860 T/C polymorphism is associated with the immune response to interferon (IFN) therapy, which is applied in the treatment of chronic viral hepatitis induced by hepatitis B virus (HBV) and hepatitis C virus (HCV).	0.008957582	2014	IFNL3;IFNL4	19	39248147	C	T
rs12980275	24517415	282617	IFNL3	umls:C0019163	BeFree	IL28B genotype was independently associated with R for AA vs. N-AA (OR 2.70, 95% CL 1.21-6.01; P = 0.015) at rs12980275 after adjustment for sex, age, HBV genotype, baseline levels of HBV DNA and ALT.	0.008957582	2014	NA	19	39241143	A	G
rs13181	19919686	2068	ERCC2	umls:C0019163	GAD	[XPD codon 751 polymorphism modifies the risk of hepatocellular carcinoma]	0.002638474	2009	ERCC2;KLC3	19	45351661	T	A,G
rs1544410	25245883	5741	PTH	umls:C0019163	BeFree	After adjustment for gender, age at the RRT onset, RRT vintage, chronic glomerulonephritis as a cause of renal failure and mean serum parathyroid hormone level, VDR rs1544410 polymorphism was the only one significantly associated with response to hepatitis B vaccination: homozygotes AA (adjusted OR 1.50, 95% CI: 1.17-1.94, p = 0.002) had higher risk to be non-responders than GG homozygotes.	0.000271442	2015	VDR;LOC105369749	12	47846052	C	T
rs17401966	24204805	23095	KIF1B	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	KIF1B	1	10325413	A	G
rs17401966	24204805	3119	HLA-DQB1	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.011368221	2013	KIF1B	1	10325413	A	G
rs17401966	22712471	23095	KIF1B	umls:C0019163	BeFree	A recent genome-wide association study (GWAS) using chronic HBV (hepatitis B virus) carriers with and without hepatocellular carcinoma (HCC) in five independent Chinese populations found that one SNP (rs17401966) in KIF1B was associated with susceptibility to HCC.	0.001357209	2012	KIF1B	1	10325413	A	G
rs17401966	24204805	6775	STAT4	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	KIF1B	1	10325413	A	G
rs17875380	22015712	3133	HLA-E	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.00434307	2012	HLA-F	6	29723805	C	A
rs17875380	22015712	3135	HLA-G	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.000814326	2012	HLA-F	6	29723805	C	A
rs1800206	19119483	5465	PPARA	umls:C0019163	BeFree	Peroxisome proliferator-activated receptor alpha L162V polymorphism tends to occur in HBV-induced hepatocellular carcinoma and is absent in HCV-related hepatocellular carcinoma.	0.000542884	2008	PPARA	22	46218377	C	G
rs1800562	11500061	3077	HFE	umls:C0019163	BeFree	At univariate analysis, iron overload was significantly associated with both HFE mutations (P < 0.0001), whereas ongoing hepatitis B virus infection was associated with the C282Y mutation (P < 0.05).	0.011268532	2001	HFE	6	26092913	G	A
rs1800871	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	IL10	1	206773289	A	G
rs1800871	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	IL10	1	206773289	A	G
rs1800872	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	IL10	1	206773062	T	G
rs1800872	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	IL10	1	206773062	T	G
rs1800925	25658755	3596	IL13	umls:C0019163	BeFree	This study was undertaken to determine the relationship between two IL-13 gene single nucleotide polymorphisms (SNP rs1800925 and SNP rs20541) and the incidence of hepatitis B virus-related (HBV) hepatocellular carcinoma (HCC).	0.000542884	2014	IL13;LOC101927761	5	132657117	C	T
rs1883832	25547203	958	CD40	umls:C0019163	BeFree	Association of CD40 -1C/T polymorphism in the 5'-untranslated region with chronic HBV infection.	0.003452799	2014	CD40	20	46118343	T	C
rs20417	22340386	5743	PTGS2	umls:C0019163	BeFree	Cyclooxygenase-2 promoter polymorphism -899G/C is associated with hepatitis B-related liver cancer in a Chinese population of Gansu province.	0.007348794	2011	PTGS2;PACERR	1	186681189	C	G
rs20541	25658755	3596	IL13	umls:C0019163	BeFree	This study was undertaken to determine the relationship between two IL-13 gene single nucleotide polymorphisms (SNP rs1800925 and SNP rs20541) and the incidence of hepatitis B virus-related (HBV) hepatocellular carcinoma (HCC).	0.000542884	2014	IL13	5	132660272	A	G
rs2221903	23354321	27189	IL17C	umls:C0019163	BeFree	It is suggested that IL21 rs2221903 and IL21R rs3093301 polymorphisms may, independently or interactively, affect the susceptibility to and/or persistence of HBV infection potentially through altering IL-21 and IgE production.	0.000542884	2013	IL21;IL21-AS1	4	122617757	C	T
rs2221903	23354321	59067	IL21	umls:C0019163	BeFree	It is suggested that IL21 rs2221903 and IL21R rs3093301 polymorphisms may, independently or interactively, affect the susceptibility to and/or persistence of HBV infection potentially through altering IL-21 and IgE production.	0.001628651	2013	IL21;IL21-AS1	4	122617757	C	T
rs2228570	25541958	84668	FAM126A	umls:C0019163	BeFree	We conclude that the VDR rs2228570 and DBP rs7041 polymorphisms may contribute to increased susceptibility to HBV-related HCC in the Chinese population.	0.017643722	2014	VDR	12	47879112	A	T,G,C
rs2234671	23396733	84668	FAM126A	umls:C0019163	BeFree	The frequency of the risk allele 'C' for the SNP, rs2234671 was found to be insignificant when the patient group was compared to the uninfected control group, however, a significant distribution of the allele 'C' of rs2234671 was observed among active HBV carriers + cirrhosis + cirrhosis - HCC vs. inactive HBV carriers with an OR = 1.631 (95% C.I.	0.017643722	2013	CXCR1	2	218164385	C	G
rs2296651	24735529	6554	SLC10A1	umls:C0019163	BeFree	This study investigated the association of the functional polymorphism c.800C>T (p.S267F) (rs2296651) of the NTCP gene with HBV infection.	0.122171535	2015	SLC10A1	14	69778476	G	A
rs2395309	21904616	3115	HLA-DPB1	umls:C0019163	BeFree	By using logistic regression analysis, these two SNPs in the HLA-DPA1 and HLA-DPB1 genes were significantly associated with HBV infection in Han Chinese populations (P = 0.021∼3.36×10(-8) at rs2395309; P = 8.37×10(-3)∼2.68×10(-10) at rs9277535).	0.132334436	2011	NA	6	33058469	A	G
rs2395309	21904616	3113	HLA-DPA1	umls:C0019163	BeFree	By using logistic regression analysis, these two SNPs in the HLA-DPA1 and HLA-DPB1 genes were significantly associated with HBV infection in Han Chinese populations (P = 0.021∼3.36×10(-8) at rs2395309; P = 8.37×10(-3)∼2.68×10(-10) at rs9277535).	0.122714419	2011	NA	6	33058469	A	G
rs25487	24289575	7515	XRCC1	umls:C0019163	BeFree	However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified.	0.001085767	2015	XRCC1	19	43551574	T	C
rs2596542	24204805	3119	HLA-DQB1	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.011368221	2013	MICA;LOC101929072	6	31398818	C	T
rs2596542	24204805	6775	STAT4	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	MICA;LOC101929072	6	31398818	C	T
rs2596542	24010643	619501	HCC	umls:C0019163	BeFree	We demonstrated a significant contribution of MICA rs2596542G/A promoter variant and nonsynonymous substitutions MICA-129Met/Val, MICA-251Gln/Arg, MICA-175Gly/Ser, triplet repeat polymorphism and respective haplotypes with HBV-induced HCC and HBV persistence.	0.016829396	2013	MICA;LOC101929072	6	31398818	C	T
rs2596542	24204805	23095	KIF1B	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	MICA;LOC101929072	6	31398818	C	T
rs2596542	24010643	84668	FAM126A	umls:C0019163	BeFree	We demonstrated a significant contribution of MICA rs2596542G/A promoter variant and nonsynonymous substitutions MICA-129Met/Val, MICA-251Gln/Arg, MICA-175Gly/Ser, triplet repeat polymorphism and respective haplotypes with HBV-induced HCC and HBV persistence.	0.017643722	2013	MICA;LOC101929072	6	31398818	C	T
rs2834167	25032264	390928	PAPL	umls:C0019163	BeFree	Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.	0.000271442	2015	IL10RB	21	33268483	A	G
rs2834167	19714778	3586	IL10	umls:C0019163	BeFree	A recent genome-wide association study discovered that two polymorphisms, interferon (IFN) alpha receptor 2 (IFNAR-2) F8S and interleukin 10 receptor (IL10RB) K47E, were associated with susceptibility to hepatitis B virus (HBV) infection in Africa.	0.049802141	2009	IL10RB	21	33268483	A	G
rs2834167	25032264	3588	IL10RB	umls:C0019163	BeFree	Rs423058 upstream of PAPL, rs2834167 in IL10RB and rs1012068 in DEPDC5 were associated with chronic HBV status, HBV natural clearance and the presence of HCC (P = 0.0004–0.024), respectively.	0.120814326	2015	IL10RB	21	33268483	A	G
rs2834167	23745570	3588	IL10RB	umls:C0019163	BeFree	Furthermore, AA genotype of IL10RB-K47E was found to be significantly decreased in chronic HBV patients compared with individuals with self-limited HBV infection (P = 0.006, P(c)= 0.018 and OR = 0.45).	0.120814326	2013	IL10RB	21	33268483	A	G
rs2856718	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	NA	6	32702478	C	T
rs2856718	24750255	84668	FAM126A	umls:C0019163	BeFree	Our study demonstrated the clear relevance of HLA-DQ rs2856718 and rs9275572 with HBV susceptibility, natural clearance and HBV-associated HCC.	0.017643722	2015	NA	6	32702478	C	T
rs2856718	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	NA	6	32702478	C	T
rs28934571	23200676	7157	TP53	umls:C0019163	BeFree	Hepatocellular carcinoma (HCC) is associated with hepatitis B virus (HBV) chronicity and dietary exposure to aflatoxin, a mutagen targeting codon 249 of tumor suppressor TP53 (R249S mutation).	0.037065441	2013	TP53	17	7674216	C	A
rs28934571	22675488	7157	TP53	umls:C0019163	BeFree	Most HCC are associated with chronic infection by Hepatitis B Virus while a G → T mutation at codon 249 of the TP53 gene, R249S, specific for exposure to aflatoxin, is detected in tumors for up to 30% of cases.	0.037065441	2012	TP53	17	7674216	C	A
rs28934571	21768053	7157	TP53	umls:C0019163	BeFree	Seasonal variation in TP53 R249S-mutated serum DNA with aflatoxin exposure and hepatitis B virus infection.	0.037065441	2011	TP53	17	7674216	C	A
rs28934571	19376640	7157	TP53	umls:C0019163	BeFree	There is evidence that R249S occurs as the result of mutagenesis by aflatoxin in a context of HBV chronic infection.	0.037065441	2009	TP53	17	7674216	C	A
rs28934571	22759751	7157	TP53	umls:C0019163	BeFree	In regions with high prevalence of chronic hepatitis B virus (HBV) infection and dietary aflatoxin B(1) (AFB(1)) exposure, hepatocellular carcinomas (HCCs) often contain TP53 mutation at codon 249 (R249S).	0.037065441	2012	TP53	17	7674216	C	A
rs28934571	20538734	7157	TP53	umls:C0019163	BeFree	Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein.	0.037065441	2010	TP53	17	7674216	C	A
rs28934571	23886144	7157	TP53	umls:C0019163	BeFree	Hepatitis B virus genetic variation and TP53 R249S mutation in patients with hepatocellular carcinoma in Thailand.	0.037065441	2014	TP53	17	7674216	C	A
rs3077	23326374	3115	HLA-DPB1	umls:C0019163	BeFree	Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown to be associated with HBV persistence after acute HBV infection.	0.132334436	2013	HLA-DPA1	6	33065245	A	G
rs3077	25041342	3115	HLA-DPB1	umls:C0019163	BeFree	In addition, Uygurs have higher frequencies of HLA-DP/DQ protective alleles (72.5% for rs3077, 76.6% for rs9277535 and 26.8% for rs7453920) than Tibetans (51.7% for rs3077, 52.5% for rs9277535 and 18.5% for rs7453920)(all P < 0.05), and a lower prevalence of HBV infection as previously reported.	0.132334436	2014	HLA-DPA1	6	33065245	A	G
rs3077	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	HLA-DPA1	6	33065245	A	G
rs3077	23825586	3113	HLA-DPA1	umls:C0019163	BeFree	We genotyped SNPs rs3077 (near HLA-DPA1) and rs9277378 and rs3128917 (both near HLA-DPB1) in 500 HBV carriers (hepatitis B surface antigen [HBsAg]-positive), 245 non-HBV infected controls (HBsAg- and antibody to hepatitis B core protein [anti-HBc]-negative), and 259 subjects with natural HBV clearance (HBsAg-negative, anti-HBc-positive).	0.122714419	2013	HLA-DPA1	6	33065245	A	G
rs3077	23601003	3115	HLA-DPB1	umls:C0019163	BeFree	Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.	0.132334436	2014	HLA-DPA1	6	33065245	A	G
rs3077	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	HLA-DPA1	6	33065245	A	G
rs3077	22737229	3113	HLA-DPA1	umls:C0019163	GWASCAT	Genome-wide association study confirming association of HLA-DP with protection against chronic hepatitis B and viral clearance in Japanese and Korean.	0.122714419	2012	HLA-DPA1	6	33065245	A	G
rs3077	23326374	3113	HLA-DPA1	umls:C0019163	BeFree	Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown to be associated with HBV persistence after acute HBV infection.	0.122714419	2013	HLA-DPA1	6	33065245	A	G
rs3077	25103089	3113	HLA-DPA1	umls:C0019163	BeFree	Japanese patients (202) who were hepatitis B e antigen positive at baseline, received LAM as first-line treatment, and consented to HLA-DP genotyping (HLA-DPA1 rs3077 and HLA-DPB1 rs9277535) were categorized into two cohorts, viz., a cohort who achieved virological response without rescue therapy (cohort 1) and those who did so with rescue therapy (cohort 2).	0.122714419	2014	HLA-DPA1	6	33065245	A	G
rs3077	21750111	3113	HLA-DPA1	umls:C0019163	GWASCAT	A genome-wide association study of chronic hepatitis B identified novel risk locus in a Japanese population.	0.122714419	2011	HLA-DPA1	6	33065245	A	G
rs3093301	23354321	27189	IL17C	umls:C0019163	BeFree	It is suggested that IL21 rs2221903 and IL21R rs3093301 polymorphisms may, independently or interactively, affect the susceptibility to and/or persistence of HBV infection potentially through altering IL-21 and IgE production.	0.000542884	2013	IL21R	16	27429509	T	C
rs3093301	23354321	59067	IL21	umls:C0019163	BeFree	It is suggested that IL21 rs2221903 and IL21R rs3093301 polymorphisms may, independently or interactively, affect the susceptibility to and/or persistence of HBV infection potentially through altering IL-21 and IgE production.	0.001628651	2013	IL21R	16	27429509	T	C
rs3128917	23825586	3113	HLA-DPA1	umls:C0019163	BeFree	We genotyped SNPs rs3077 (near HLA-DPA1) and rs9277378 and rs3128917 (both near HLA-DPB1) in 500 HBV carriers (hepatitis B surface antigen [HBsAg]-positive), 245 non-HBV infected controls (HBsAg- and antibody to hepatitis B core protein [anti-HBc]-negative), and 259 subjects with natural HBV clearance (HBsAg-negative, anti-HBc-positive).	0.122714419	2013	NA	6	33092219	T	G
rs31777	21656577	2264	FGFR4	umls:C0019163	BeFree	We genotyped four FGFR4 SNPs (rs351855, rs641101, rs376618, and rs31777) in 1,451 Chinese subjects, including 711 patients with HCC, 368 controls with HBV infection and 372 controls without HBV infection, using the TaqMan genotyping assay.	0.000271442	2012	FGFR4	5	177096561	C	A
rs346473	21823009	83478	ARHGAP24	umls:C0019163	BeFree	Effects of variant rs346473 in ARHGAP24 gene on disease progression of HBV infection in Han Chinese population.	0.000542884	2014	ARHGAP24	4	85980468	G	A
rs351855	21656577	2264	FGFR4	umls:C0019163	BeFree	We genotyped four FGFR4 SNPs (rs351855, rs641101, rs376618, and rs31777) in 1,451 Chinese subjects, including 711 patients with HCC, 368 controls with HBV infection and 372 controls without HBV infection, using the TaqMan genotyping assay.	0.000271442	2012	FGFR4	5	177093242	G	A
rs352140	25388852	54106	TLR9	umls:C0019163	BeFree	To investigate whether single nucleotide polymorphisms (SNPs) in Toll-like receptors (TLRs) 3 and 9 affect the susceptibility of hepatitis B virus (HBV) intrauterine transmission, we genotyped 399 neonates for TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).	0.001900093	2015	TLR9	3	52222681	C	A,T
rs352140	25388852	7098	TLR3	umls:C0019163	BeFree	To investigate whether single nucleotide polymorphisms (SNPs) in Toll-like receptors (TLRs) 3 and 9 affect the susceptibility of hepatitis B virus (HBV) intrauterine transmission, we genotyped 399 neonates for TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).	0.002171535	2015	TLR9	3	52222681	C	A,T
rs369560944	24141768	139818	DOCK11	umls:C0019163	BeFree	The highly conserved ATG S5 was mutated to ACG by T378C, which led to the substitution sM75T and inhibition of the production and secretion of the hepatitis B surface antigen (HBsAg), and subsequent inhibition of HBV replication.	0.000542884	2013	DOCK11	X	118543579	T	C
rs3746444	24854593	574501	MIR499A	umls:C0019163	BeFree	The risk of HCC was significantly higher with miR-499 rs3746444 TC+CC genotypes compared with those with the TT genotype (odds ratio [OR]=1.372, 95% confidence intervals [CI]=1.099-1.713, p=0.005), as was the risk of hepatitis B virus-related HCC (OR=1.437, 95% CI=1.128-1.831, p=0.003).	0.001085767	2015	MYH7B;MIR499A;MIR499B	20	34990448	A	G
rs376618	21656577	2264	FGFR4	umls:C0019163	BeFree	We genotyped four FGFR4 SNPs (rs351855, rs641101, rs376618, and rs31777) in 1,451 Chinese subjects, including 711 patients with HCC, 368 controls with HBV infection and 372 controls without HBV infection, using the TaqMan genotyping assay.	0.000271442	2012	FGFR4	5	177090796	C	T
rs3775290	25388852	54106	TLR9	umls:C0019163	BeFree	To investigate whether single nucleotide polymorphisms (SNPs) in Toll-like receptors (TLRs) 3 and 9 affect the susceptibility of hepatitis B virus (HBV) intrauterine transmission, we genotyped 399 neonates for TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).	0.001900093	2015	TLR3	4	186083063	C	T,A
rs3775290	25388852	7098	TLR3	umls:C0019163	BeFree	To investigate whether single nucleotide polymorphisms (SNPs) in Toll-like receptors (TLRs) 3 and 9 affect the susceptibility of hepatitis B virus (HBV) intrauterine transmission, we genotyped 399 neonates for TLR3 (c.1377C/T) [rs3775290] and TLR9 (G2848A) [rs352140] using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP).	0.002171535	2015	TLR3	4	186083063	C	T,A
rs3803012	23868705	5901	RAN	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	RAN	12	130876170	A	C,G
rs3803012	23868705	23405	DICER1	umls:C0019163	BeFree	We observed that DICER1 rs1057035 CT/CC variant genotypes were associated with a significant decreased risk of HCC (adjusted OR = 0.79, 95% CI = 0.64-0.96) compared with wild-type TT and RAN rs3803012 AG/GG variant genotypes increased the risk of HBV persistent infection compared with AA genotype (adjusted OR = 1.35, 95% CI = 1.03-1.77).	0.000271442	2013	RAN	12	130876170	A	C,G
rs3803012	23868705	9271	PIWIL1	umls:C0019163	BeFree	These findings indicated that DICER1 rs1057035, RAN rs3803012, and PIWIL1 rs10773771 might contribute to the risk of HBV-related HCC.	0.000271442	2013	RAN	12	130876170	A	C,G
rs3806798	24762213	3600	IL15	umls:C0019163	BeFree	In conclusion, we found an association between IL-15 rs3806798 and the risk of chronic HBV infection in a sample of Chinese Han population.	0.000542884	2014	IL15	4	141636126	T	A
rs386493716	24289575	7515	XRCC1	umls:C0019163	BeFree	However, no potential contribution of XRCC1 Arg399Gln polymorphism to HCC susceptibility in HBV/HCV subgroups was identified.	0.001085767	2015	NA	NA	NA	NA	NA
rs386574522	23745570	3588	IL10RB	umls:C0019163	BeFree	Furthermore, AA genotype of IL10RB-K47E was found to be significantly decreased in chronic HBV patients compared with individuals with self-limited HBV infection (P = 0.006, P(c)= 0.018 and OR = 0.45).	0.120814326	2013	NA	NA	NA	NA	NA
rs386574522	19714778	3586	IL10	umls:C0019163	BeFree	A recent genome-wide association study discovered that two polymorphisms, interferon (IFN) alpha receptor 2 (IFNAR-2) F8S and interleukin 10 receptor (IL10RB) K47E, were associated with susceptibility to hepatitis B virus (HBV) infection in Africa.	0.049802141	2009	NA	NA	NA	NA	NA
rs41557518	22015712	3135	HLA-G	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.000814326	2012	HLA-G	6	29828658	C	-
rs41557518	22015712	3133	HLA-E	umls:C0019163	BeFree	Four SNPs (rs17875380, rs41557518, rs114465251, and rs115492845) were associated with altered susceptibility to HBV or HCC, and HLA-F01:04, HLA-G01:05N, and HLA-E*01:01 were associated with hepatitis B or hepatitis B complicated with HCC.	0.00434307	2012	HLA-G	6	29828658	C	-
rs430397	19533686	3309	HSPA5	umls:C0019163	GAD	[allele A and genotypes AA and AG of rs430397 may represent high risk and poor prognosis for HCC.]	0.008630058	2009	HSPA5	9	125238840	C	T
rs430397	21779363	3309	HSPA5	umls:C0019163	BeFree	Our previous study indicated that a common variant (rs430397 G>A) in the intron 5 of glucose-regulated protein 78 (GRP78) gene was associated with risk and prognosis of primary hepatocellular carcinoma (HCC), including HBV- and cirrhosis-related HCC.	0.008630058	2011	HSPA5	9	125238840	C	T
rs4309483	24995424	406906	MIR122	umls:C0019163	BeFree	These findings indicate that the C to A base change of rs4309483 may alter the expression of miR-122, thus providing protective effect from chronic HBV infection but an increased risk for HCC in HBV carriers.	0.004614512	2014	NA	18	58418685	A	C
rs4444903	22236006	1950	EGF	umls:C0019163	BeFree	Carriage of the EGF rs4444903 A>G functional polymorphism associates with disease progression in chronic HBV infection.	0.001357209	2012	EGF	4	109912954	A	G
rs4821116	24162738	7332	UBE2L3	umls:C0019163	GWASCAT	These findings highlight the importance of HLA-C and UBE2L3 in the clearance of HBV infection in addition to HLA-DP and HLA-DQ.	0.120271442	2013	UBE2L3	22	21619030	C	T
rs4986790	23093310	7099	TLR4	umls:C0019163	BeFree	Toll like receptor 4 D299G associates with disease progression in Caucasian patients with chronic HBV infection: relationship with gender.	0.004810009	2013	TLR4	9	117713024	A	G
rs4986790	18666712	7099	TLR4	umls:C0019163	BeFree	By use of a polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) analysis technique, we genotyped Toll-like receptor 4 (TLR4) Asp299Gly and Thr399Ile and CD14-159 and -260 polymorphisms in 110 HBV-related cirrhotic patients and 110 healthy controls from the Chinese Han population.	0.004810009	2008	TLR4	9	117713024	A	G
rs4986790	22740716	7099	TLR4	umls:C0019163	BeFree	Toll-like receptor 4 rs4986790 (p.Asp299Gly) was associated with HBsAg seroclearance/seroconversion in chronic HBV patients.	0.004810009	2012	TLR4	9	117713024	A	G
rs4986791	18666712	7099	TLR4	umls:C0019163	BeFree	By use of a polymerase chain reaction-based restriction fragment length polymorphism (PCR-RFLP) analysis technique, we genotyped Toll-like receptor 4 (TLR4) Asp299Gly and Thr399Ile and CD14-159 and -260 polymorphisms in 110 HBV-related cirrhotic patients and 110 healthy controls from the Chinese Han population.	0.004810009	2008	TLR4	9	117713324	C	T
rs56061981	24023775	3627	CXCL10	umls:C0019163	BeFree	G-201A in promoter region of IP-10 gene was associated with liver disease progression in patients with HBV infection through up-regulating IP-10 expression.	0.005167327	2013	ART3;CXCL10	4	76023632	C	T
rs568408	20521253	3592	IL12A	umls:C0019163	BeFree	Our findings indicate that IL12A rs568408 may contribute to the risk of HCC and modify HCC risk associated with HBV infection.	0.000814326	2011	IL12A;IL12A-AS1	3	159995680	G	A
rs619586	22493738	378938	MALAT1	umls:C0019163	BeFree	We conducted a case-control study and genotyped two SNPs, rs7763881 in HULC and rs619586 in MALAT1, in 1300 HBV positive HCC patients, 1344 HBV persistent carriers and 1344 subjects with HBV natural clearance to test the associations between the two SNPs and susceptibility to HCC and HBV chronic infection.	0.000271442	2012	MALAT1	11	65498698	A	G
rs636832	25239527	26523	AGO1	umls:C0019163	BeFree	Our study first provided the evidence that rs636832 in AGO1 was associated with chronic HBV infection susceptibility in Chinese Han population.	0.000271442	2014	AGO1	1	35897874	G	A
rs641101	21656577	2264	FGFR4	umls:C0019163	BeFree	We genotyped four FGFR4 SNPs (rs351855, rs641101, rs376618, and rs31777) in 1,451 Chinese subjects, including 711 patients with HCC, 368 controls with HBV infection and 372 controls without HBV infection, using the TaqMan genotyping assay.	0.000271442	2012	FGFR4;LOC105377749	5	177086459	A	G
rs6513497	25177719	84668	FAM126A	umls:C0019163	BeFree	Compared with the T allele of rs6513497, the G allele was associated with a significantly decreased risk of HCC (OR = 0.788, 95% CI = 0.631-0.985, P = 0.037); moreover, a more protective effect of the G allele was shown in males (OR = 0.695, 95% CI = 0.539-0.897, P = 0.005 in HCC and OR = 0.739, 95% CI = 0.562-0.972, P = 0.030 in HBV-related HCC), basically in a dominant manner (HCC: OR = 0.681, 95% CI = 0.162-0.896, P = 0.006; HBV-related HCC: OR = 0.715, 95% CI = 0.532-0.962, P = 0.027).	0.017643722	2014	MIR646HG;MIR646	20	60308547	T	G
rs6684439	24668548	3569	IL6	umls:C0019163	BeFree	The present study supports the view that variants in the rs6684439 SNP of IL-6R is associated with a lower risk of HBV-related HCC, and this could provide valuable clues to understanding the mechanisms underlying susceptibility to this malignant disease.	0.017078432	2014	IL6R	1	154423363	C	T
rs7041	25541958	84668	FAM126A	umls:C0019163	BeFree	We conclude that the VDR rs2228570 and DBP rs7041 polymorphisms may contribute to increased susceptibility to HBV-related HCC in the Chinese population.	0.017643722	2014	GC	4	71752617	A	C
rs7453920	25041342	3115	HLA-DPB1	umls:C0019163	BeFree	In addition, Uygurs have higher frequencies of HLA-DP/DQ protective alleles (72.5% for rs3077, 76.6% for rs9277535 and 26.8% for rs7453920) than Tibetans (51.7% for rs3077, 52.5% for rs9277535 and 18.5% for rs7453920)(all P < 0.05), and a lower prevalence of HBV infection as previously reported.	0.132334436	2014	HLA-DQB2	6	32762235	A	G
rs7453920	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	HLA-DQB2	6	32762235	A	G
rs7453920	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	HLA-DQB2	6	32762235	A	G
rs7574865	24204805	3119	HLA-DQB1	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.011368221	2013	STAT4	2	191099907	T	G
rs7574865	24204805	6775	STAT4	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	STAT4	2	191099907	T	G
rs7574865	24204805	23095	KIF1B	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	STAT4	2	191099907	T	G
rs7763881	22493738	378938	MALAT1	umls:C0019163	BeFree	We conducted a case-control study and genotyped two SNPs, rs7763881 in HULC and rs619586 in MALAT1, in 1300 HBV positive HCC patients, 1344 HBV persistent carriers and 1344 subjects with HBV natural clearance to test the associations between the two SNPs and susceptibility to HCC and HBV chronic infection.	0.000271442	2012	HULC;LOC100506207	6	8653014	A	C
rs7770370	25389088	3115	HLA-DPB1	umls:C0019163	BeFree	SNP rs7770370 in HLA-DPB1 loci as a major genetic determinant of response to booster hepatitis B vaccination: results of a genome-wide association study.	0.132334436	2014	HLA-DPA1;HLA-DPB1	6	33081144	A	G
rs8099917	25664396	282617	IFNL3	umls:C0019163	BeFree	In conclusion, these results suggested a IL28B rs8099917T allele predispose for susceptibility to chronic HBV infection but not leading to HCC in Thai population.	0.008957582	2014	NA	19	39252525	T	G
rs8099917	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	NA	19	39252525	T	G
rs8099917	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	NA	19	39252525	T	G
rs9275319	24204805	3119	HLA-DQB1	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.011368221	2013	NA	6	32698518	A	G
rs9275319	24204805	23095	KIF1B	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	NA	6	32698518	A	G
rs9275319	24204805	6775	STAT4	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	NA	6	32698518	A	G
rs9275572	24204805	84668	FAM126A	umls:C0019163	BeFree	These findings provided convincing evidence that rs9275572 significantly associated with HBV-related HCC.	0.017643722	2013	NA	6	32711222	A	G
rs9275572	24204805	6775	STAT4	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	NA	6	32711222	A	G
rs9275572	24204805	23095	KIF1B	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.001357209	2013	NA	6	32711222	A	G
rs9275572	24204805	3119	HLA-DQB1	umls:C0019163	BeFree	Genome-wide association studies (GWAS) have identified three loci (rs17401966 in KIF1B, rs7574865 in STAT4, rs9275319 in HLA-DQ) as being associated with hepatitis B virus-related hepatocellular carcinoma (HBV-related HCC) in a Chinese population, two loci (rs2596542 in MICA, rs9275572 located between HLA-DQA and HLA-DQB) with hepatitis C virus-related HCC (HCV-related HCC) in a Japanese population.	0.011368221	2013	NA	6	32711222	A	G
rs9275572	24750255	84668	FAM126A	umls:C0019163	BeFree	Our study demonstrated the clear relevance of HLA-DQ rs2856718 and rs9275572 with HBV susceptibility, natural clearance and HBV-associated HCC.	0.017643722	2015	NA	6	32711222	A	G
rs9277378	23825586	3113	HLA-DPA1	umls:C0019163	BeFree	We genotyped SNPs rs3077 (near HLA-DPA1) and rs9277378 and rs3128917 (both near HLA-DPB1) in 500 HBV carriers (hepatitis B surface antigen [HBsAg]-positive), 245 non-HBV infected controls (HBsAg- and antibody to hepatitis B core protein [anti-HBc]-negative), and 259 subjects with natural HBV clearance (HBsAg-negative, anti-HBc-positive).	0.122714419	2013	HLA-DPA1;HLA-DPB1	6	33082502	A	G
rs9277535	21904616	3113	HLA-DPA1	umls:C0019163	BeFree	By using logistic regression analysis, these two SNPs in the HLA-DPA1 and HLA-DPB1 genes were significantly associated with HBV infection in Han Chinese populations (P = 0.021∼3.36×10(-8) at rs2395309; P = 8.37×10(-3)∼2.68×10(-10) at rs9277535).	0.122714419	2011	HLA-DPB1	6	33087084	A	G
rs9277535	23326374	3115	HLA-DPB1	umls:C0019163	BeFree	Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown to be associated with HBV persistence after acute HBV infection.	0.132334436	2013	HLA-DPB1	6	33087084	A	G
rs9277535	19349983	3115	HLA-DPB1	umls:C0019163	GWASCAT	Our findings show that genetic variants in the HLA-DP locus are strongly associated with risk of persistent infection with hepatitis B virus.	0.132334436	2009	HLA-DPB1	6	33087084	A	G
rs9277535	19349983	3115	HLA-DPB1	umls:C0019163	GAD	[Our findings show that genetic variants in the HLA-DP locus are strongly associated with risk of persistent infection with hepatitis B virus.]	0.132334436	2009	HLA-DPB1	6	33087084	A	G
rs9277535	22737229	3115	HLA-DPB1	umls:C0019163	GWASCAT	To clarify the pathogenesis of CHB and the mechanisms of HBV clearance, further studies are necessary, including functional analyses of the HLA-DP molecule.	0.132334436	2012	HLA-DPB1	6	33087084	A	G
rs9277535	25376093	282617	IFNL3	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.008957582	2014	HLA-DPB1	6	33087084	A	G
rs9277535	23601003	3115	HLA-DPB1	umls:C0019163	BeFree	Association of the rs3077 and rs9277535 polymorphisms in HLA-DP with hepatitis B virus infection and spontaneous clearance: a meta-analysis.	0.132334436	2014	HLA-DPB1	6	33087084	A	G
rs9277535	25041342	3115	HLA-DPB1	umls:C0019163	BeFree	In addition, Uygurs have higher frequencies of HLA-DP/DQ protective alleles (72.5% for rs3077, 76.6% for rs9277535 and 26.8% for rs7453920) than Tibetans (51.7% for rs3077, 52.5% for rs9277535 and 18.5% for rs7453920)(all P < 0.05), and a lower prevalence of HBV infection as previously reported.	0.132334436	2014	HLA-DPB1	6	33087084	A	G
rs9277535	23326374	3113	HLA-DPA1	umls:C0019163	BeFree	Two single nucleotide polymorphisms (SNP), rs3077 near HLA-DPA1 region and rs9277535 near HLA-DPB1 region, have been shown to be associated with HBV persistence after acute HBV infection.	0.122714419	2013	HLA-DPB1	6	33087084	A	G
rs9277535	24659896	3126	HLA-DRB4	umls:C0019163	BeFree	A phylogenetic analysis revealed that the isolated HBV was genotype H. In this patient, the elevated peak level of HBV-DNA and the risk alleles at human genome single nucleotide polymorphisms s3077 and rs9277535 in the human leukocyte antigen-DP locus were considered to be risk factors for chronic infection.	0.004071628	2013	HLA-DPB1	6	33087084	A	G
rs9277535	21750111	3115	HLA-DPB1	umls:C0019163	GWASCAT	These findings indicated that variants in antigen-binding regions of HLA-DP and HLA-DQ contribute to the risk of persistent HBV infection.	0.132334436	2011	HLA-DPB1	6	33087084	A	G
rs9277535	25376093	3119	HLA-DQB1	umls:C0019163	BeFree	This was a retrospective cohort study.We genotyped seven SNPs in the following genes, interleukin (IL)-10 (rs1800871 and rs1800872), human leukocyte antigen (HLA)-DPA1 (rs3077), HLA-DPB1 (rs9277535), HLA-DQB2 (rs7453920), HLA-DQB1 (rs2856718), and IL28B (rs8099917), in patients with chronic HBV infection using PCR and sequencing.	0.011368221	2014	HLA-DPB1	6	33087084	A	G
rs9277535	25103089	3113	HLA-DPA1	umls:C0019163	BeFree	Japanese patients (202) who were hepatitis B e antigen positive at baseline, received LAM as first-line treatment, and consented to HLA-DP genotyping (HLA-DPA1 rs3077 and HLA-DPB1 rs9277535) were categorized into two cohorts, viz., a cohort who achieved virological response without rescue therapy (cohort 1) and those who did so with rescue therapy (cohort 2).	0.122714419	2014	HLA-DPB1	6	33087084	A	G
rs9277535	21904616	3115	HLA-DPB1	umls:C0019163	BeFree	By using logistic regression analysis, these two SNPs in the HLA-DPA1 and HLA-DPB1 genes were significantly associated with HBV infection in Han Chinese populations (P = 0.021∼3.36×10(-8) at rs2395309; P = 8.37×10(-3)∼2.68×10(-10) at rs9277535).	0.132334436	2011	HLA-DPB1	6	33087084	A	G

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:186)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
6	30766204	rs3129987	T	C	rs3129987	23760081	2.28E-08	GWAS stage only	2.86	[1.89-4.35]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30800326	rs3130648	C	T	rs3130648	23760081	1.78E-08	GWAS stage only	2.38	[1.72-3.23]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30853796	rs3131034	G	A	rs3131034	23760081	2.08E-08	GWAS stage only	2.38	[1.69-3.23]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30872203	rs3130779	A	G	rs3130779	23760081	4.06E-08	GWAS stage only	2.33	[1.67-3.23]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30874308	rs3130780	T	G	rs3130780	23760081	5.22E-08	GWAS stage only	2.27	[1.67-3.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30895444	rs2532932	A	G	rs2532932	23760081	7.26E-09	GWAS stage only	2.44	[1.75-3.45]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30897022	rs2517459	T	C	rs2517459	23760081	3.28E-08	GWAS stage only	2.27	[1.67-3.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	30900094	rs2253705	T	C	rs2253705	23760081	3.13E-08	GWAS stage only	2.33	[1.67-3.23]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	31117075	rs1265115	C	A	rs1265115	23760081	1.98E-08	GWAS stage only	1.61	[1.37-1.92]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	31130593	rs1419881	G	A	rs1419881	23760081	1.00E-18	GWAS + replication	1.37	[1.23-1.52]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	31851234	rs652888	A	G	rs652888	23760081	7.00E-13	GWAS + replication	1.38	[1.22-1.57]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	31863433	rs2243873	C	A	rs2243873	23760081	1.65E-08	GWAS stage only	1.75	[1.44-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32398202	rs9268589	G	A	rs9268589	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32398563	rs7774047	C	A	rs7774047	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32400070	rs9268606	G	A	rs9268606	23760081	6.63E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32400538	rs9268607	A	G	rs9268607	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32400865	rs9268608	C	T	rs9268608	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32402440	rs7753264	A	G	rs7753264	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32402692	rs9268613	C	T	rs9268613	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32402889	rs9268615	G	A	rs9268615	23760081	6.43E-08	GWAS stage only	1.56	[1.33-1.85]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32408527	rs9268645	C	G	rs9268645	23760081	2.87E-08	GWAS stage only	1.59	[1.35-1.89]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32441100	rs9269081	A	C	rs9269081	23760081	2.87E-08	GWAS stage only	1.59	[1.33-1.89]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32581647	rs9271303	A	G	rs9271303	23760081	1.26E-09	GWAS stage only	1.67	[1.41-1.97]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32581778	rs2395223	C	T	rs2395223	23760081	1.26E-09	GWAS stage only	1.67	[1.41-1.97]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32582275	rs2858859	G	A	rs2858859	23760081	1.41E-09	GWAS stage only	1.67	[1.41-1.97]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32582332	rs5004276	G	A	rs5004276	23760081	1.26E-09	GWAS stage only	1.67	[1.41-1.97]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32582513	rs9271325	C	G	rs9271325	23760081	4.20E-08	GWAS stage only	1.59	[1.34-1.87]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32626311	rs6906021	T	C	rs6906021	23760081	6.99E-08	GWAS stage only	1.56	[1.33-1.84]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32634341	rs3189152	A	G,T	rs3189152	23760081	1.55E-09	GWAS stage only	1.67	[1.41-1.97]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32636866	rs3134996	A	T	rs3134996	23760081	3.78E-09	GWAS stage only	1.82	[1.49-2.27]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32657351	rs2395535	A	C	rs2395535	23760081	1.01E-08	GWAS stage only	1.64	[1.37-1.96]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32657505	rs4538748	T	C	rs4538748	23760081	1.01E-08	GWAS stage only	1.64	[1.37-1.96]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32663631	rs3129720	T	C	rs3129720	23760081	5.58E-08	GWAS stage only	2	[1.54-2.63]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32665616	rs2856664	G	T	rs2856664	23760081	2.84E-09	GWAS stage only	1.63	[1.39-1.92]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32665741	rs2646996	A	G	rs2646996	23760081	2.84E-09	GWAS stage only	1.63	[1.39-1.92]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32666721	rs2856726	A	T	rs2856726	23760081	2.83E-09	GWAS stage only	1.63	[1.39-1.92]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32667230	rs2858312	G	C	rs2858312	23760081	4.51E-09	GWAS stage only	1.62	[1.38-1.91]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32668411	rs9275373	G	A	rs9275373	23760081	1.47E-09	GWAS stage only	2.38	[1.75-3.23]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32668657	rs2856720	C	T	rs2856720	23760081	7.13E-09	GWAS stage only	1.61	[1.37-1.90]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32668704	rs2647047	C	G	rs2647047	23760081	6.40E-09	GWAS stage only	1.62	[1.37-1.91]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32669767	rs2647050	T	C	rs2647050	23760081	6.12E-10	GWAS stage only	1.67	[1.41-1.96]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32670255	rs2856718	C	T	rs2856718	23760081	2.00E-24	GWAS + replication	1.6	[1.46-1.75]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32671014	rs2856704	C	A	rs2856704	23760081	5.75E-09	GWAS stage only	1.62	[1.37-1.91]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32685911	rs3104399	T	A	rs3104399	23760081	6.64E-08	GWAS stage only	2.08	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32698899	rs7751699	G	A	rs7751699	23760081	6.39E-08	GWAS stage only	2.13	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32702498	rs9276279	C	T	rs9276279	23760081	5.20E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32703021	rs9276298	G	A	rs9276298	23760081	5.56E-08	GWAS stage only	2.13	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32703206	rs9276302	A	G	rs9276302	23760081	4.22E-10	GWAS stage only	2.44	[1.82-3.33]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32705002	rs9276319	C	T	rs9276319	23760081	5.48E-08	GWAS stage only	2.13	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32706234	rs7773068	G	A	rs7773068	23760081	4.85E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32706334	rs7773694	A	G	rs7773694	23760081	5.48E-08	GWAS stage only	2.13	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32706480	rs7755597	C	T	rs7755597	23760081	4.85E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32707295	rs9276370	G	T	rs9276370	24940741	2.00E-12	NA	1.95	[1.62-2.34]	321 Chinese ancestry cases; 304 Chinese ancestry controls	Chinese(625)	ALL(625)	ASN(625)	ALL(625)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	rs9276370-T	Research Support, Non-U.S. Gov't
6	32708467	rs9276394	T	A	rs9276394	23760081	5.48E-08	GWAS stage only	2.13	[1.59-2.78]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32708504	rs9276395	C	G	rs9276395	23760081	5.60E-09	GWAS stage only	2.27	[1.69-3.03]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32708736	rs9276396	T	C	rs9276396	23760081	4.85E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32709363	rs2051598	G	A	rs2051598	23760081	4.53E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32711857	rs9276427	T	C	rs9276427	23760081	1.83E-09	GWAS stage only	1.89	[1.54-2.38]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32713188	rs2213565	C	T	rs2213565	23760081	3.05E-08	GWAS stage only	2.13	[1.61-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32716022	rs2213573	G	A	rs2213573	23760081	4.59E-08	GWAS stage only	2.13	[1.59-2.86]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32718162	rs9276482	C	T	rs9276482	23760081	1.00E-08	GWAS stage only	2	[1.56-2.56]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32723917	rs7756516	C	T	rs7756516	24940741	1.48E-11	NA	1.87	[1.56-2.25]	321 Chinese ancestry cases; 304 Chinese ancestry controls	Chinese(625)	ALL(625)	ASN(625)	ALL(625)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	rs7756516-T	Research Support, Non-U.S. Gov't
6	32729459	rs2071551	C	T	rs2071551	23760081	4.31E-09	GWAS stage only	2.04	[1.59-2.56]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32729642	rs762815	G	C	rs762815	23760081	2.62E-09	GWAS stage only	2.08	[1.61-2.70]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32729821	rs7768538	C	A	rs7768538	23760081	4.08E-09	GWAS stage only	2.04	[1.59-2.63]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32729880	rs9276583	G	A	rs9276583	23760081	3.72E-08	GWAS stage only	1.92	[1.52-2.50]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32730012	rs7453920	A	G	rs7453920	23760081	7.00E-26	GWAS + replication	2	[1.72-2.27]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32730012	rs7453920	A	G	rs7453920	24940741	7.00E-15	NA	2.31	[1.87-2.85]	321 Chinese ancestry cases; 304 Chinese ancestry controls	Chinese(625)	ALL(625)	ASN(625)	ALL(625)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	rs7453920-G	Research Support, Non-U.S. Gov't
6	32730086	rs2051549	G	A	rs2051549	23760081	4.67E-09	GWAS stage only	2.04	[1.59-2.63]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32786882	rs3763355	T	C	rs3763355	23760081	3.25E-09	GWAS stage only	2.38	[1.75-3.33]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32786917	rs3763354	G	A	rs3763354	23760081	4.08E-10	GWAS stage only	2.44	[1.79-3.33]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32796793	rs4148876	G	A	rs4148876	23760081	9.19E-10	GWAS stage only	2.5	[1.82-3.45]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32803316	rs4148871	A	G	rs4148871	23760081	3.60E-08	GWAS stage only	2.04	[1.56-2.63]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	32900018	rs154977	C	G	rs154977	23760081	6.32E-10	GWAS stage only	2	[1.59-2.56]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33024654	rs3135402	A	C	rs3135402	23760081	2.80E-09	GWAS stage only	1.69	[1.43-2.04]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33025174	rs9380335	C	G	rs9380335	23760081	4.31E-11	GWAS stage only	1.75	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33026087	rs7741912	C	G	rs7741912	23760081	1.89E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33026110	rs422544	A	C	rs422544	23760081	1.12E-10	GWAS stage only	1.79	[1.49-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33026246	rs2395309	A	G	rs2395309	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33026553	rs34937821	G	A	rs34937821	23760081	3.88E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33030441	rs9469325	C	A	rs9469325	23760081	4.26E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33031602	rs9469329	C	T	rs9469329	23760081	2.52E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33032188	rs17214519	G	A	rs17214519	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33033022	rs3077	A	G	rs3077	23760081	5.00E-39	GWAS + replication	1.89	[1.69-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33033351	rs7751953	G	T	rs7751953	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33034785	rs9469331	G	A	rs9469331	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33034876	rs9469332	T	C	rs9469332	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33035877	rs9469341	A	G	rs9469341	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33035969	rs3179779	A	G	rs3179779	23760081	2.44E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33036177	rs3180554	A	G	rs3180554	23760081	4.73E-11	GWAS stage only	1.75	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33036210	rs3180553	G	T	rs3180553	23760081	3.53E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33036435	rs1126769	T	G	rs115259770	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33036999	rs1042190	T	C	rs1042190	23760081	1.67E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33037187	rs3830066	C	G	rs3830066	23760081	4.71E-11	GWAS stage only	1.75	[1.49-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33037265	rs36081724	C	A	rs36081724	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33037424	rs1126542	T	A,C,G	rs1126542	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33037580	rs2308911	T	G	rs2308911	23760081	2.37E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33037675	rs10214910	C	A	rs10214910	23760081	2.71E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33038369	rs2301224	C	A	rs2301224	23760081	1.02E-11	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33038766	rs2301220	C	T	rs2301220	23760081	2.60E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33039295	rs28452918	T	A	rs28452918	23760081	4.26E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33039686	rs13213149	T	C	rs13213149	23760081	1.64E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040596	rs4640928	A	G	rs4640928	23760081	1.64E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040715	rs6914849	G	A	rs6914849	23760081	8.96E-12	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040736	rs9380336	T	C	rs9380336	23760081	1.12E-11	GWAS stage only	1.82	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040744	rs6914995	G	C	rs6914995	23760081	1.64E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040798	rs9380338	T	C	rs9380338	23760081	1.64E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33040835	rs9348904	A	G	rs9348904	23760081	1.94E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33041034	rs1431399	A	C,G,T	rs1431399	23760081	1.02E-11	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33041073	rs9357156	A	C	rs9357156	23760081	2.66E-09	GWAS stage only	1.67	NA	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33041176	rs1431400	C	T	rs1431400	23760081	1.35E-11	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33041186	rs1431401	G	A	rs1431401	23760081	9.15E-12	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33043930	rs2071351	A	G	rs2071351	23760081	1.64E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33044257	rs2071353	T	C	rs2071353	23760081	1.07E-10	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33046662	rs2567279	T	C	rs2567279	23760081	1.74E-08	GWAS stage only	1.69	[1.41-2.04]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33047031	rs1431403	T	C	rs1431403	23760081	3.95E-10	GWAS stage only	1.72	[1.45-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33048686	rs1042169	G	A,T	rs76513735	23760081	2.62E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33048694	rs553665868	A	G	rs9277356	23760081	2.17E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33048921	rs7770370	A	G	rs7770370	23760081	7.44E-09	GWAS stage only	1.64	[1.38-1.94]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33049211	rs928976	C	T	rs928976	23760081	1.33E-10	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33049979	rs9277357	A	G	rs9277357	23760081	2.31E-10	GWAS stage only	1.72	[1.45-2.04]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050024	rs9277359	C	A	rs9277359	23760081	1.77E-10	GWAS stage only	1.72	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050279	rs9277378	A	G	rs9277378	23760081	7.59E-11	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050499	rs9277386	A	G	rs9277386	23760081	1.68E-11	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050742	rs3128961	G	A	rs3128961	23760081	9.05E-11	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050829	rs9277392	G	C	rs9277392	23760081	2.14E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33050970	rs9277394	A	T	rs9277394	23760081	1.61E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051051	rs9277395	A	G	rs9277395	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051139	rs9277396	G	A	rs9277396	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051624	rs9277409	C	G	rs9277409	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051640	rs9277410	G	A	rs9277410	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051777	rs9277419	A	G	rs9277419	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051910	rs9277426	C	A,G,T	rs9277426	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33051976	rs9277428	T	A	rs9277428	23760081	2.11E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33052072	rs9277432	A	T	rs9277432	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33052250	rs9277437	A	G	rs9277437	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053167	rs9277458	A	C	rs9277458	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053271	rs9277462	T	C	rs9277462	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053307	rs9277463	C	T	rs9277463	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053352	rs9277464	C	T	rs9277464	23760081	3.29E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053455	rs9277468	C	T	rs9277468	23760081	1.56E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053468	rs9277469	G	T	rs9277469	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053682	rs9277471	G	A	rs9277471	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053723	rs9277472	T	C	rs9277472	23760081	1.62E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053772	rs9277477	G	A	rs9277477	23760081	1.53E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053789	rs9277479	A	G	rs9277479	23760081	1.15E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053812	rs9277480	A	G	rs9277480	23760081	3.39E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053906	rs9277488	G	T	rs9277488	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33053982	rs9277492	G	C	rs9277492	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054071	rs9277495	G	C	rs9277495	23760081	8.55E-12	GWAS stage only	1.82	[1.52-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054268	rs9277515	C	A	rs9277515	23760081	3.10E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054457	rs1042544	A	G	rs1042544	23760081	1.22E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054721	rs9277533	C	T	rs9277533	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054807	rs9277534	A	G	rs9277534	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054861	rs9277535	A	G	rs9277535	23760081	4.00E-40	GWAS + replication	1.89	[1.72-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33054861	rs9277535	A	G	rs9277535	24940741	5.00E-14	NA	1.59	[1.41-1.79]	321 Chinese ancestry cases; 304 Chinese ancestry controls	Chinese(625)	ALL(625)	ASN(625)	ALL(625)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	rs9277535-G	Research Support, Non-U.S. Gov't
6	33055047	rs9277538	A	G	rs9277538	23760081	1.74E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055123	rs9277540	A	G	rs9277540	23760081	1.09E-11	GWAS stage only	1.82	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055158	rs9277541	A	G	rs9277541	23760081	1.82E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055247	rs9277542	T	C	rs9277542	23760081	1.73E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055346	rs9277546	T	G	rs9277546	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055367	rs9277547	C	A	rs9277547	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055419	rs9277549	A	G	rs9277549	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055487	rs9277550	T	C	rs9277550	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055494	rs9277551	G	T	rs9277551	23760081	2.05E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055538	rs9277554	C	T	rs9277554	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055780	rs3128963	C	T	rs3128963	23760081	1.53E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055818	rs3128964	A	G	rs3128964	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33055844	rs201709182	T	TTATC	rs5875436	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056069	rs3117229	G	A	rs3117229	23760081	3.29E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056207	rs3130186	C	T	rs3130186	23760081	3.29E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056253	rs3128968	T	A	rs3128968	23760081	1.08E-10	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056435	rs3117228	G	T	rs3117228	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056566	rs3091281	T	C	rs3091281	23760081	3.29E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056694	rs9277557	T	C	rs9277557	23760081	3.29E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056711	rs9277558	C	T	rs9277558	23760081	2.84E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33056916	rs9277566	G	T	rs9277566	23760081	5.03E-12	GWAS stage only	1.82	[1.54-2.17]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057055	rs9277568	T	C	rs9277568	23760081	1.80E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057176	rs3130188	T	C	rs3130188	23760081	1.53E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057198	rs3091282	G	C	rs3091282	23760081	1.37E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057440	rs3097650	C	T	rs3097650	23760081	8.83E-11	GWAS stage only	1.75	[1.47-2.08]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057711	rs3117225	G	A	rs3117225	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33057835	rs3097652	C	T	rs3097652	23760081	1.48E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33063403	rs3117216	A	G	rs3117216	23760081	2.11E-11	GWAS stage only	1.79	[1.49-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33073322	rs2064476	A	G	rs2064476	23760081	1.73E-11	GWAS stage only	1.79	[1.52-2.13]	400 Korean ancestry cases; 1,000 Korean ancestry controls	Korean(1400)	ALL(1400)	ASN(1400)	ALL(1400)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	NA	Research Support, Non-U.S. Gov't
6	33104175	rs9366816	T	C	rs9366816	24940741	3.00E-10	NA	1.43	[1.28-1.60]	321 Chinese ancestry cases; 304 Chinese ancestry controls	Chinese(625)	ALL(625)	ASN(625)	ALL(625)	Chronic hepatitis B infection	HPOID:0006562	HPOID:0200123	Viral hepatitis	Chronic hepatitis	DOID:2043	hepatitis B	NA	NA	EFOID:0004197	chronic hepatitis B infection	Hepatitis B	rs9366816-C	Research Support, Non-U.S. Gov't

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Chemical(Total Drugs:10)
CUI	ChemicalName	ChemicalID	CasRN	DiseaseName	DiseaseID	DirectEvidence	PubMedIDs
C0019163	cyclophosphamide	D003520	50-18-0	hepatitis b	MESH:D006509	marker/mechanism	19008178
C0019163	entecavir	C413685	-	hepatitis b	MESH:D006509	therapeutic	12121928
C0019163	famciclovir	C060590	104227-87-4	hepatitis b	MESH:D006509	therapeutic	10418752
C0019163	ganciclovir	D015774	82410-32-0	hepatitis b	MESH:D006509	therapeutic	10601065
C0019163	indomethacin	D007213	53-86-1	hepatitis b	MESH:D006509	therapeutic	15784032
C0019163	peginterferon alfa-2a	C100416	-	hepatitis b	MESH:D006509	therapeutic	16448446
C0019163	penciclovir	C053539	-	hepatitis b	MESH:D006509	therapeutic	10353255
C0019163	ritonavir	D019438	-	hepatitis b	MESH:D006509	therapeutic	10357637
C0019163	tenofovir	D000068698	-	hepatitis b	MESH:D006509	therapeutic	12519935
C0019163	zidovudine	D015215	30516-87-1	hepatitis b	MESH:D006509	therapeutic	10948398

FDA approved drug and dosage information(Total Drugs:14)
DiseaseID	Drug_name	active_ingredients	strength	Dosage Form/Route	Marketing Status	TE code	RLD	RS
MESH:D006509	norvir	ritonavir	80MG/ML	SOLUTION;ORAL	Prescription	None	Yes	Yes
MESH:D006509	norvir	ritonavir	100MG	CAPSULE;ORAL	Discontinued	None	No	No
MESH:D006509	norvir	ritonavir	100MG	CAPSULE;ORAL	Prescription	None	Yes	Yes
MESH:D006509	norvir	ritonavir	100MG	TABLET;ORAL	Prescription	AB	Yes	Yes
MESH:D006509	retrovir	zidovudine	100MG	CAPSULE;ORAL	Prescription	AB	Yes	Yes
MESH:D006509	retrovir	zidovudine	50MG/5ML	SYRUP;ORAL	Prescription	AA	Yes	Yes
MESH:D006509	retrovir	zidovudine	10MG/ML	INJECTABLE;INJECTION	Prescription	AP	Yes	Yes
MESH:D006509	retrovir	zidovudine	200MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D006509	zidovudine	zidovudine	60MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D006509	zidovudine	zidovudine	60MG	TABLET;ORAL	Discontinued	None	No	No
MESH:D006509	famvir	famciclovir	250MG	TABLET;ORAL	Discontinued	None	Yes	No
MESH:D006509	famvir	famciclovir	250MG	TABLET;ORAL	Discontinued	None	Yes	No
MESH:D006509	baraclude	entecavir	0.5MG	TABLET;ORAL	Prescription	AB	Yes	No
MESH:D006509	baraclude	entecavir	0.05MG/ML	SOLUTION;ORAL	Prescription	None	Yes	Yes

FDA labeling changes(Total Drugs:14)
DiseaseID	Pediatric_Labeling_Date	Trade_Name	Generic_Name_or_Proper_Name	Indications Studied	Label Changes Summary	Product Labeling	BPCA(B)	PREA(P)	BPCA(B) and PREA(P)	Pediatric Rule (R)	Sponsor	Pediatric Exclusivity Granted Date	NNPS
MESH:D006509	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D006509	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D006509	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D006509	6/10/2005	norvir	ritonavir	Treatment of HIV-infection in combination with other antiretroviral agents	Extended age range from 2 years down to 1 month AE profile in the pediatric population was similar to that for adults Information on dose and PK parameters	Labeling	B	-	-	-	Abbott	06/14/2005	FALSE'
MESH:D006509	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	09/19/2008	retrovir syrup, capsules and tablets	zidovudine	Used in combination with 18 other antiretroviral agents for the treatment of HIV-1 infection	Dosing and administration information provided to children 6 weeks to less than 18 years of age Macrocytosis was reported in the majority of pediatric patients receiving Retrovir 180 mg/m2 every 6 hours in open-label studies New dosing regimen	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	6/11/2009	retrovir	zidovudine	Treatment of HIV-1 infection in combination with other antiretroviral agents	Provided dosing recommendations for patients 4 weeks to < 6 weeks of age and weighing 4 kg to < 9 kg	Labeling	-	P	-	-	GlaxoSmithKline	-	TRUE'
MESH:D006509	12/24/2009	famvir	famciclovir	Treatment of children 1 month 12 years of age w/ herpes simplex (HSV) & 1 12 years w/ varicella zoster (VSV)	Available data are insufficient to support the use of famciclovir for the treatment of children with chickenpox or infections due to HSV The PK profile and safety were studied in 2 open-label studies: (1) a single-dose PK and safety study in infants 1 month to	Labeling	-	-	B, P	-	Novartis	09/21/2009	FALSE'
MESH:D006509	9/2/2012	famvir	famciclovir	Recurrent herpes labialis	Efficacy has not been established in pediatric patients for the treatment of recurrent herpes labialis Information on an open label PK, safety and efficacy study in children 12 to	Labeling	-	P	-	-	Novartis	-	-
MESH:D006509	03/20/2014	baraclude	entecavir	Treatment of chronic hepatitis B virus (HBV) infection	Approved for use in pediatric patients 2 years and older Safety and effectiveness have not been established in pediatric patients less than 2 years. Use in this age group has not been evaluated because treatment of HBV in this age group is rarely required There are limited data available on the use of Baraclude in lamivudine-experienced pediatric patients Adverse reactions in clinical trials were similar to those observed in adults Information on dosing in pediatric patients 2 years and weighing at least 10 kg, adverse reactions, PK parameters and clinical trials New dosage form	Labeling	-	-	B,P	-	Bristol-Myers Squibb	-	FALSE'
MESH:D006509	03/20/2014	baraclude	entecavir	Treatment of chronic hepatitis B virus (HBV) infection	Approved for use in pediatric patients 2 years and older Safety and effectiveness have not been established in pediatric patients less than 2 years. Use in this age group has not been evaluated because treatment of HBV in this age group is rarely required There are limited data available on the use of Baraclude in lamivudine-experienced pediatric patients Adverse reactions in clinical trials were similar to those observed in adults Information on dosing in pediatric patients 2 years and weighing at least 10 kg, adverse reactions, PK parameters and clinical trials New dosage form	Labeling	-	-	B,P	-	Bristol-Myers Squibb	-	FALSE'